Week 1
Because Microdosing begins below standard dosing, the body may have time to adjust gradually with milder side effects for some.4
Weight & Longevity
Microdosing Semaglutide Rx
A low dose GLP-1 approach designed to work in sync with your body, which may support moderate weight loss and cravings while minimizing side effects.
Starting at
$99
/ mo
- Monthly, 2-mo, and 4-mo plans
- Starting price applies to 4-mo plans
- US-licensed pharmacies
- Pause or cancel anytime
A gentle, lower dose way to approach GLP-1 for those who don’t need extremes
May support appetite, cravings, and food noise¹ ²
Personalized by a licensed provider to minimize side effects
HSA / FSA
Ongoing, expert support
Free, discreet shipping
100% online
Frequently asked questions
How do you microdose with Semaglutide?
Microdosing Semaglutide uses lower amounts than standard dosing. Your provider will guide your plan and help you understand how to measure your dose correctly. The goal is the lowest dose that delivers benefits while minimizing side effects, not the highest dose you can manage.
Can I transition from Microdosing to a regular dose if needed?
Yes. If your goals change or you need more support, your provider can help determine whether a full-dose GLP-1 prescription may be a better fit.
Is Microdosing Semaglutide a full-dose GLP-1?
No. Microdosing Semaglutide uses lower amounts than standard GLP-1 dosing and is designed for adults seeking a gentler, clinician-guided approach.
Usage instructions
View all FAQs
Microdosing Semaglutide is self-administered according to your provider-guided titration schedule. If prescribed, a US-licensed provider will provide a tailored dosage schedule and specific treatment instructions with your care plan.
Important safety information and common side effects
Microdosing Semaglutide medication may include glycine, an amino acid intended to support cellular function and metabolism.
Do not use with other GLP-1 receptor agonist medications, or any other products containing GLP-1s.
Side effects
Microdosing GLP-1 is a low dose injectable GLP-1 prescription (Tirzepatide or Semaglutide).
Compounded GLP-1s have not been evaluated by the FDA, but side effects are expected to be similar to other GLP-1-based medications reviewed by the FDA, which have the following side effects: nausea, diarrhea, vomiting, constipation, abdominal (stomach) pain, headache, fatigue, dyspepsia (indigestion), dizziness, abdominal distension, eructation (belching), hypoglycemia (low blood sugar), flatulence (gas buildup), gastroenteritis (an intestinal infection), and gastroesophageal reflux disease (a type of digestive disorder).
Common side effects normally go away on their own within a few days or up to 2-3 weeks. Read our blog for more tips on how to manage GLP-1 side effects. If you find that any side effects persist for longer than this or get worse over time, stop taking your medication and contact your provider as soon as possible. For a full list of side effects, please review the Mayo Clinic’s Semaglutide and Tirzepatide resources.
Other important safety information
Do not use GLP-1s if you have a personal or family history of medullary thyroid carcinoma (MTC), multiple endocrine neoplasia syndrome 2 (MEN2), or pancreatitis.
Do not use GLP-1s if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed.
Though rare, allergic reactions to GLP-1 medications are possible. If you notice any shortness of breath or swelling around your face, tongue, or throat after using GLP-1s, stop using the medication immediately and contact emergency services right away.
As with any prescription medicine, the dose prescribed is for you and you alone. Do not, under any circumstances, allow anyone else to use your prescription.
Tell your healthcare provider about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Tell your healthcare provider if you are taking any medications to treat diabetes, including sylfonylureas or insulin.
Note: The above statements have not been evaluated by the Food and Drug Administration. This product alone is not intended to diagnose, treat, cure, or prevent any disease. Please consult a medical professional to determine whether or not Microdosing Semaglutide is appropriate for you.
Disclaimer
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. Actual product packaging may appear differently than shown.
What is Microdosing Semaglutide?
(sem-uh-GLOO-tide)Not everyone needs full doses of GLP-1. Microdosing Semaglutide uses smaller doses than standard GLP-1 dosing, designed to work in sync with the body instead of flooding it all at once.
For those who want support with moderate weight goals, appetite, and food noise, Microdosing may offer a lower-dose way to begin GLP-1 care without extremes.1 2 3
10 lbs average weight loss by 6 months
10lbs
Actual results may vary. Data was self-reported by 4,582 surveyed customers who checked in with their provider on their second and third check-in between 6/1/2025-7/17/2026. All respondents are AgelessRx Microdosing customers who were approved for a prescription after completing an assessment with a medical provider.
How Microdosing Semaglutide works
1 Month
As dose and routine settle, food noise and cravings may begin to feel easier to manage with provider support along the way.1 2
3 Months
Some are settling into their maintenance dose, with appetite and cravings potentially starting to feel more manageable.
6 Months
With consistent use, some may see moderate weight changes alongside shifts in appetite, energy, inflammatory symptoms, and how in control they feel day to day.1 2 5
1 Year and Beyond
Support continues as your goals evolve, whether that means maintaining progress, adjusting your plan, or deciding what level of support fits next.
Week 1
Because Microdosing begins below standard dosing, the body may have time to adjust gradually with milder side effects for some.4
1 Month
As dose and routine settle, food noise and cravings may begin to feel easier to manage with provider support along the way.1 2
3 Months
Some are settling into their maintenance dose, with appetite and cravings potentially starting to feel more manageable.
6 Months
With consistent use, some may see moderate weight changes alongside shifts in appetite, energy, inflammatory symptoms, and how in control they feel day to day.1 2 5
1 Year and Beyond
Support continues as your goals evolve, whether that means maintaining progress, adjusting your plan, or deciding what level of support fits next.
Our GLP-1 research is shaping what comes next
Most GLP-1 care focuses on doing more. We’re studying what happens when the goal is finding the right amount.
We’re running one of the first longevity-focused clinical trials on GLP-1 microdosing, led by our Stanford PhD-led Research Team. With a fully in-house care team, longevity researchers, and 40+ science-backed protocols, we’re built to support the bigger picture of your health.
We’re running one of the first longevity-focused clinical trials on GLP-1 microdosing, led by our Stanford PhD-led Research Team. With a fully in-house care team, longevity researchers, and 40+ science-backed protocols, we’re built to support the bigger picture of your health.
One of the first longevity-focused clinical trials on GLP-1 microdosing
Stanford PhD-led Research Team behind 11+ longevity clinical trials and 9 peer-reviewed publications
Fully in-house medical team with 199+ years of combined clinical experience
Unlimited provider messaging for side effects, dose questions, refills, and next steps
Subscribe & save
GLP-1 care that starts with you
One-size-fits-all is one-size-fits-none. You deserve a plan that meets you where you are, and gets you to where you want to be.
$99/month
Applies to 4-month plan billed in full ($159/mo after)
What’s included
-
Personalized, clinician-guided plan
-
Monthly, 2-month, and 4-month plans
-
Dispensed by US-licensed compounding pharmacy
-
Unlimited protocol adjustments and messaging
-
Ongoing support and check-ins
-
Pause or cancel anytime
-
Backed by our in-house Stanford PhD-led team
Clinically studied
The science of Microdosing GLP-1
Semaglutide acts on a single, well-characterized target—the GLP-1 receptor—and has been studied longer and more extensively than any other GLP-1 molecule available. Commonly used to treat type 2 diabetes and weight management, GLP-1 medications act on GLP-1 receptors located in the brain, gut, and immune system, impacting multiple biomarkers.6
In a series of studies, low doses of GLP-1 receptor agonists were shown to modulate inflammatory pathways, support mitochondrial function, and lower risk factors for cognitive decline in study participants—giving Microdosing GLP-1 promising potential for extending healthspan.5 7 8
In a series of studies, low doses of GLP-1 receptor agonists were shown to modulate inflammatory pathways, support mitochondrial function, and lower risk factors for cognitive decline in study participants—giving Microdosing GLP-1 promising potential for extending healthspan.5 7 8
How it works
Choosing how you age starts here
1
Clinician-led
Connect with a clinician
Connect with one of our US-licensed, in-house medical providers with 199+ years of combined clinical experience to make sure treatment is right for you. 100% online. No in-person visit required.
2
Fast, discreet shipping
Get your discreet shipment
If approved, your treatment is compounded by a US-licensed, LegitScript-certified pharmacy partner, rigorously inspected for quality, and shipped discreetly to your door.
3
100% online
Receive continuous support
Start with one goal, then keep building over time. With our in-house care team, unlimited provider messaging, easy refills, unlimited dosage adjustments, and 40+ science-backed plans, your care evolves with you.
Get Started
Disclaimer
The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. See above for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.
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Frequently asked questions
Semaglutide works with the GLP-1 pathway, which is involved in appetite, fullness, food intake, and metabolic response.⁶ Microdosing uses lower amounts than standard dosing, with provider-guided adjustments over time.
Microdosing Semaglutide may be a fit for those seeking moderate weight support, help with appetite or food noise, or a gentler way to begin GLP-1 care.¹ ² ³
Microdosing is not designed to match full-dose GLP-1 weight loss. Full-dose GLP-1s are dosed to maximize weight loss; microdosing is dosed to find the minimum amount that may deliver metabolic and craving-related benefits while minimizing side effects. It’s intended for people seeking a lower-dose approach for moderate weight loss and more long-term health goals.
At full doses, Semaglutide acts on a single pathway, GLP-1, and has the longer track record, including a large trial showing meaningful cardiovascular risk reduction. Tirzepatide acts on two pathways, GLP-1 and GIP, and tends to produce somewhat greater appetite suppression at comparable standard doses.⁹
Microdosing Semaglutide is typically taken once weekly by subcutaneous injection, only as prescribed by your provider. If approved you will receive a personalized dosing schedule based on your health history and goals.
Houston, we have
citations.
We vet everything on PubMed so you don’t have to. Here’s what the science says.