Our commitment to longevity research

AgelessRx Observational Initiative
Active

AgelessRx Observational Initiative

Observed Changes in Various Longevity Monitoring Tools in Patients on Diverse Interventions

This program is designed to generate a better understanding of how AgelessRx therapies affect various longevity-centered endpoints. The observational initiative is open to all willing and eligible patients within the AgelessRx community.

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Active, not recruiting

Rapamycin Trial

Participatory Evaluation of Aging with Rapamycin for Longevity (PEARL)

Rapamycin is an FDA-approved antifungal agent, most used to prevent organ transplant rejection. Rapamycin targets the mTOR signaling pathway, which is associated with many aging-related diseases.

PEARL is a double-blind, randomized, placebo-controlled trial. Notably, it is the first nationwide telemedicine trial and the first large-scale intervention trial on longevity. PEARL is proudly sponsored by AgelessRx and affiliated with the University of California.

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Rapamycin Trial
LDN Registry
Completing, pending analysis

LDN Registry

The Effects of Low Dose Naltrexone (LDN) on Diseases of Aging

Are you currently taking LDN? If yes, participate in our LDN Registry to help us collect valuable information on the benefits you’re experiencing! This trial aims to provide prescribers and the entire longevity community with better-informed usage insight on LDN as a longevity therapy.

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Completing, pending analysis

Post-COVID-19 Trial

Pilot Study into Low Dose Naltrexone (LDN) and NAD+ for Treatment of Patients with Post-COVID-19 Syndrome

Proudly sponsored by AgelessRx, this double-blind placebo-controlled pilot study will assess the use of Low Dose Naltrexone (LDN) and NAD+ for the treatment of patients with post-COVID-19 syndrome (long-COVID-19).

AgelessRx will enroll over 60 people (must have had a positive test for SARS-CoV-2 1-4 months before enrollment) for a 12-week study. Patients will receive LDN and NAD+ treatment or a corresponding placebo tablet and patch (control group) for the 12-week duration.

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Post-COVID-19 Trial