Advanced, clinician-guided plans for skin, hair, desire, and sexual health—designed to target the root cause so you can feel like the best version of you.
When attraction is still there but desire isn’t, support the brain pathways behind arousal and responsiveness—helping intimacy feel more natural again.
Starting at$149/ mo
Tadalafil
Support stronger, longer-lasting erections for up to 36 hours with the same active ingredient in Cialis®, so intimacy can fit your life instead of the other way around.
Starting at$45/ mo
PT-141 Nasal Spray
New
When attraction is still there but desire isn’t, support the brain pathways behind arousal and responsiveness with a fast-acting, needle-free option for men and women.
Starting at$149/ mo
NAD+ Face Cream
Supports smoother, brighter, firmer-looking skin with a clinician-guided formula that delivers pure NAD+ to address visible signs of aging.
Starting at$95/ mo
GHK-Cu Cream
New
Support firmer, smoother-looking skin with a naturally occurring copper peptide that helps restore the repair and renewal processes that decline with age.
Starting at$99/ mo
DMAE Firming Gel
An exclusive Rx-compounded 3% gel, combining DMAE with hyaluronic and alpha lipoic acids for firmer, smoother-looking skin—built on the idea that skin ages at the cellular level, not just the surface.
Starting at$68/ mo
Tretinoin
Prescription-strength retinoid that may support skin renewal and collagen for smoother lines, firmer-looking skin, and more refined texture beyond over-the-counter retinol.
Starting at$70/ mo
Powers Hair Solution v5.1
The latest from world-renowned Dr. William Powers, this exclusive formula features minoxidil and dutasteride, with 9 other synergistic ingredients, proven to reduce thinning and promote hair regrowth for men and women.
Starting at $95
It’s not about being 25 again. It’s about feeling your best.
You can take care of yourself, invest in quality products, and still notice changes—because most of what is sold treats the symptoms, not the signaling behind it.1 2 3
We target the root cause of why these happen in the first place with science, so you can go beneath the surface to feel your best, no matter your age.
Actual results may vary. Data was self-reported by 1,756 surveyed DMAE Firming Gel, NAD+ Face Cream, and Tretinoin customers who checked in with their provider on their second check-in, 111 surveyed Powers Hair Solution Customers and 626 Tadalafil customers who checked in with their provider on their third check-in between 4/11/22-2/5/26. All respondents are AgelessRx customers who were approved for a prescription after completing an assessment with a medical provider.
What’s changing beneath the surface
2 Weeks
Your treatment gets to work on the cellular signaling behind skin renewal, hair growth, blood flow, or desire—the mechanism, not just the symptom.1 2 3
30 Days
The work is happening underneath the surface, targeting the cellular mechanisms behind skin, hair, and sexual health.
3 Months
Early wins may be easier to spot: smoother-looking skin, fuller hair, or a more reliable sexual response and satisfaction.4 5 6
6 Months
Consistency starts paying off, with results that feel less occasional and more like your new normal.
1 Year and Beyond
You’re no longer guessing. You have a proven, expert-guided routine that addresses the actual mechanism behind what’s changed, helping you keep looking, feeling, and connecting at your best.
2 Weeks
Your treatment gets to work on the cellular signaling behind skin renewal, hair growth, blood flow, or desire—the mechanism, not just the symptom.1 2 3
30 Days
The work is happening underneath the surface, targeting the cellular mechanisms behind skin, hair, and sexual health.
3 Months
Early wins may be easier to spot: smoother-looking skin, fuller hair, or a more reliable sexual response and satisfaction.4 5 6
6 Months
Consistency starts paying off, with results that feel less occasional and more like your new normal.
1 Year and Beyond
You’re no longer guessing. You have a proven, expert-guided routine that addresses the actual mechanism behind what’s changed, helping you keep looking, feeling, and connecting at your best.
Disclaimer
The above statements have not been evaluated by the Food and Drug Administration. These product(s) are not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. See above for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.
Actual results may vary. Data was self-reported by 713 surveyed DMAE Firming Gel customers and 442 surveyed NAD+ Face Cream customers who checked in with their provider on their second check-in between 4/11/22-2/5/26. All respondents are AgelessRx customers who were approved for a prescription after completing an assessment with a medical provider.
Find the right sexual health treatment
PT-141 Injection
Starting at $149/mo
PT-141 Nasal Spray
Starting at $149/mo
Tadalafil
Starting at $45/mo
Delivery
Injection
Nasal Spray
Pill
Frequency
As needed
As needed
As Needed
Benefits
Supports low desire and more noticeable support⁴
Supports sexual health with a needle-free option¹⁰
Advanced care backed by a Stanford PhD-led Research Team
With our fully in-house Medical, Research, and Customer Care teams, every protocol is vetted for safety, efficacy, and being on the forefront of longevity science.
I just wish that someone had told me that desire and performance are not the same thing.
Antonio
I love AgelessRx. I check in regularly with my doctor to see how I am doing on my regimen. I feel amazing. My skin has never looked better. No more Botox for me!! I no longer need it. I feel as if I’m aging backwards.
Tammy
Desire can change with age.
Misty
Everything is going great. My skin is brighter and younger looking.
Anthony
Deciding to make the choice to order from AgelessRx was the start but now feeling energized, my skin feeling hydrated and my mood being drastically improved, it was the best choice for myself!!!!
Isabel
I liked that PT 141 works through the brain where desire actually begins.
Davita
I'm currently using NAD+, Glutathione, Infinite, B12/MIC, Tadalafil and LDN. I FEEL AMAZING! I'm going to be 55 in June. I feel like a 25 year old athlete…My wife has noticed my physical change and also the magic in the bedroom.
Grover
I just wish that someone had told me that desire and performance are not the same thing.
Antonio
I love AgelessRx. I check in regularly with my doctor to see how I am doing on my regimen. I feel amazing. My skin has never looked better. No more Botox for me!! I no longer need it. I feel as if I’m aging backwards.
Tammy
Desire can change with age.
Misty
Everything is going great. My skin is brighter and younger looking.
Anthony
Deciding to make the choice to order from AgelessRx was the start but now feeling energized, my skin feeling hydrated and my mood being drastically improved, it was the best choice for myself!!!!
Isabel
I liked that PT 141 works through the brain where desire actually begins.
Davita
I'm currently using NAD+, Glutathione, Infinite, B12/MIC, Tadalafil and LDN. I FEEL AMAZING! I'm going to be 55 in June. I feel like a 25 year old athlete…My wife has noticed my physical change and also the magic in the bedroom.
Grover
Individual results may vary. Testimonials are not a guarantee of future results.
You can’t out-routine your biology
More effort on the same surface-level routine won’t target a cause with deeper biological roots.
Advanced, clinician-guided treatments may help target the biological pathways behind what’s changing at the cellular level, so you can finally find answers.
Tell us what you want to see, feel, or change. A licensed clinician reviews your goals, health history, and routine to help identify the treatment, strength, and format that fits you.
Your body’s clock is running 6 years younger than your chronological age.
Skin, Hair & Sexual Health educational content medically reviewed by our experts
Dr. Jenell Decker, MD
Medical Director
Trusted expert in preventative care, integrative medicine, and longevity driven clinical practice.
Marshall University Joan C. Edwards School of Medicine
East Carolina University
Concord University
Frequently asked questions
01Can I combine multiple skincare treatments, like Tretinoin, DMAE, or GHK-Cu Cream, in one routine?
Yes! Many of our members want more than one treatment in their routine, and that instinct makes sense—each acts on a different part of skin cell signaling, so layering support tends to work better than relying on one product alone. The catch is trying to apply every active at full strength every night, which tends to cause irritation rather than better results.
A simple approach is alternating nights and slowly build up to daily use: Tretinoin on some evenings, something gentler like GHK-Cu Cream or DMAE Firming Gel on others, or a moisturizer applied as a buffer between steps. Your AgelessRx provider can help you sequence a routine so each product has room to work.
02What's the difference between prescription-grade skincare and over-the-counter products?
Prescription-grade formulas use higher, clearly disclosed concentrations of active ingredients than what’s available over the counter, and they’re compounded to tighter purity standards. That’s part of why a treatment like Tretinoin can work through skin’s layers more directly than a similar over-the-counter retinol, which the body has to convert into its active form after it’s applied.⁹ Prescription strength isn’t automatically the right fit for everyone, which is why a provider evaluation helps determine the formula and concentration that make sense for your skin.
03What actually causes hair thinning as we age, and can it be treated without a transplant?
Hair thinning is rarely caused by just one thing. Hormonal shifts, the hair growth cycle naturally shortening with age, ongoing stress, or nutrient gaps can all play a role.2 Most of this responds to consistent, non-surgical treatment rather than requiring a transplant. Clinical-grade hair products work on several fronts at once, supporting follicle health and helping maintain a balanced scalp environment for growth.6 Results build gradually, and your provider will monitor your progress and adjust your plan as needed.
04What's the difference between PT-141 and Tadalafil for sexual health?
PT-141 and Tadalafil support two different systems. PT-141 may work upstream, in the brain, on the signals behind desire and arousal.4 Tadalafil may work downstream, in the body, supporting blood flow for physical response.⁸ If the underlying issue is desire itself, additional blood flow support won’t address that, and the reverse is also true. That’s exactly the kind of distinction worth discussing with your provider, who can help determine which treatment actually matches what you’re experiencing.
Frankly my dear, I do give a damn about citations.
We vet everything on PubMed so you don’t have to. Here’s what the science says.
1
This study found that collagen production in chronologically aged skin is reduced due to age-related changes, declining progressively from the mid-20s onward.
2
This review found that androgenetic alopecia and age-related hair thinning result from a combination of hormonal shifts, a shortening hair growth cycle, stress, and nutrient status.
3
This study found that age-related decline in brain dopamine signaling is associated with reduced dopamine, changes linked to desire and arousal.
4
This review examines bremelanotide for hypoactive sexual desire disorder in women, showing clinical improvements in desire, arousal, and orgasm scores compared to placebo across multiple trials.
5
This review surveys cosmetic peptides and their mechanisms for combating skin aging by boosting collagen production, reducing wrinkles, and improving delivery through the skin barrier.
6
This comprehensive review found low-dose oral minoxidil shows a promising, dose-dependent safety and efficacy profile for treating male and female pattern hair loss.
7
This placebo-controlled study in men with erectile dysfunction showed that Tadalafil produced a significant response within 30 minutes of dosing, with over half of men achieving successful intercourse in that window.
8
This review found that over-the-counter retinol must undergo enzymatic conversion in the skin to become active retinoic acid, unlike prescription Tretinoin, which is already in its active form.
9
This review found that over-the-counter retinol must undergo enzymatic conversion in the skin to become active retinoic acid, unlike prescription Tretinoin, which is already in its active form.
10
This review explains that epigenetic changes—such as DNA methylation and histone modifications—help regulate how aging occurs and may link genetic, environmental, and lifestyle factors to age-related diseases.