Skip to content
Testing & Tracking
Core Longevity Panel
Core Longevity Panel
Core Longevity Panel

Core Longevity Panel Rx

Measure 40+ biomarkers across heart, metabolic, liver, kidney, inflammation, bone, and blood health, including advanced markers your annual labs may not routinely cover.

Get Started
40+ biomarkers across seven core health areas
Optional Lp(a) for deeper heart health insights¹
Clinician order, blood draw, and digital results included
HSA / FSA
Nationwide lab network
Clinician-reviewed results
Ongoing, expert support
Frequently asked questions
What does the Core Longevity Panel test for?

The panel looks at 40+ biomarkers, grouped into the systems that actually interact with each other: five cardiovascular markers (ApoB, LDL, HDL, triglycerides, and total cholesterol), four metabolic markers (glucose, insulin, HbA1c, and HOMA-IR), plus liver and kidney function markers, and a full CBC covering 14 additional markers tied to immune function, inflammation, and nutrient status. These aren’t read in isolation—your cardiovascular, inflammatory, and metabolic markers are connected, and your report explains how, rather than listing them as unrelated numbers the way a standard workup does.2

How does the Core Longevity Panel testing process work?

It’s a simple three-step process: order the panel, complete your blood draw at a local lab using the requisition we generate for you, and wait for your results. A physician reviews everything before it lands in your AgelessRx portal, typically within one to two weeks, alongside the full PDF readout straight from the lab.

How is the Core Longevity Panel different from the bloodwork I get at my annual physical?

A standard physical usually covers the basics. This panel goes further into markers like ApoB and HOMA-IR, which can flag heart and metabolic risk earlier than they typically show up on a routine screening and connect them into a single picture of where your risk is actually concentrated, not a list of isolated flags.3 4 It’s meant to work alongside your primary care relationship, filling in some of the gaps a standard checkup tends to miss.

Usage instructions

Core Longevity Panel is an in-person blood test completed at your local lab. If prescribed, a US-licensed medical provider will provide specific instructions with your care plan.

View all FAQs
Important safety information and common side effects

The information you learn from the Core Longevity Panel is not designed to independently diagnose, prevent, or treat any condition or disease. This test is intended for research, informational, and educational purposes only. While information might point to a diagnosis or to a possible treatment, it should always be confirmed and supplemented by additional medical and clinical testing and information. We urge you to seek the advice of your physician or healthcare provider if you have questions or concerns arising from your test results.

You should not change your health behaviors solely on the basis of information from the Core Longevity Panel. Make sure to discuss your information, and any possible desired changes, with a physician or other healthcare provider before you act.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Disclaimer

Products require an online evaluation with a licensed medical professional who will determine if testing is appropriate.

What the Core Longevity Panel measures

01 Blood & bone health

Evaluate blood cells, platelets, hemoglobin, calcium, and alkaline phosphatase for broader health insights.

02 Blood sugar & metabolism

Measure glucose, HbA1c, fasting insulin, and HOMA-IR to understand blood sugar control and insulin resistance.

03 Heart health

See ApoB, LDL, HDL, triglycerides, and optional Lp(a) for a deeper view of cardiovascular health.

04 Inflammation

Measure hs-CRP, a marker of systemic inflammation that adds context to heart and overall health.7

05 Liver & kidney health

Review key markers of liver function, kidney filtration, electrolyte balance, and waste removal.

What is the Core Longevity Panel?

You’re made of trillions of cells, and almost everything about how you feel and how you’re aging comes down to how well they’re functioning.5 6 

Analyze 40+ heart, metabolic, inflammation, organ-health, bone, and blood markers in one simple test, helping you understand where you need to focus.

Get Started

One test. Full body picture.

Know more about where you stand

Better baseline
Better health
0
key biomarkers measured
0
core health areas analyzed
0
weeks to digital results

Your annual labs are only the beginning

Annual labs can tell you whether a few numbers fall within range. The Core Longevity Panel goes deeper, bringing together advanced markers across heart health, blood sugar, inflammation, liver, kidneys, blood, and bone health so you can understand where you stand and what may deserve attention next.
Includes ApoB, fasting insulin, HOMA-IR, and hs-CRP—markers not included in routine labs
Physician order and laboratory blood draw included
40+ biomarkers organized into one easy-to-read report with findings linked to next steps
Read our Research

Read our clinical trials

XPRIZE Healthspan Competition

AgelessRx is one of 40 global teams competing to develop interventions that protect function and extend healthy years—part of our broader commitment to turning prevention science into real-world care.
Read our Research

Clinically studied

The science of blood markers

No single biomarker tells the full story. Looking at heart, metabolic, inflammatory, liver, kidney, bone, and blood markers together provides a more connected view of your health.

ApoB reflects the number of atherogenic lipoprotein particles and may improve cardiovascular-risk assessment beyond LDL cholesterol alone.3

HOMA-IR combines fasting glucose and insulin to estimate insulin resistance, while hs-CRP provides information about systemic inflammation.4 7

The upgraded panel also measures Lp(a), a primarily inherited marker with an established association with heart disease, that most routine panels never check.1

Get Started

Personalized for you

Start with your baseline

Your report brings more than 40 results into one place, helping you see where your markers stand today and which areas may be worth discussing with your healthcare provider. Repeat testing can also help you observe how your biomarkers change as your routines, health goals, or interventions evolve.
Get Started
How it works

Choosing how you age starts here

Disclaimer

The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. See above for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Actual product packaging may appear differently than shown.
Dr Jenell Decker

Core Longevity Panel educational content medically reviewed by our experts

Dr. Jenell Decker, MD

Medical Director

Trusted expert in preventative care, integrative medicine, and longevity driven clinical practice.
Marshall University Joan C. Edwards School of Medicine
East Carolina University
Concord University

Frequently asked questions

01 What happens after I get my results for the Core Longevity Panel?

Once your results are in, you’ll get an easy-to-read report in your portal breaking down what each marker means, alongside the full lab PDF for your records. From there, one of our in-house experts can help translate those numbers into an actual plan—connecting specific patterns to specific interventions, whether that means adjusting lifestyle factors, exploring a treatment like a targeted Microdosing GLP-1, NAD+, Glutathione, or LDN, or simply tracking a marker over time to see how it moves.

02 How does the Core Longevity Panel work?

After you order, AgelessRx generates the physician-ordered requisition required to complete your labs. Schedule your blood draw at a convenient date and time, then receive your digital results within two weeks.

Fast for at least eight hours before your appointment, consuming only water. Scheduling your blood draw in the morning may make fasting easier.

03 What is the difference between the two panels?

Both options measure 40+ biomarkers. The $115 panel also includes Lp(a), a largely inherited marker associated with cardiovascular risk that may not be included in routine bloodwork.

04 What is Lp(a)?

Short for lipoprotein(a), Lp(a) is a unique molecule produced by the liver. It shares similarities with LDL (low-density lipoprotein), which is commonly recognized as “bad cholesterol.” However, what sets Lp(a) apart is the addition of an apolipoprotein(a).1

Our bodies try to clean as much LDL from our bodies as possible, but this additional protein acts like a mask, disguising Lp(a) from our cells so they’re harder to clear from our bloodstream. This means Lp(a) particles are much more likely to stick around in the blood, get into blood vessel walls, and cause plaque formation, leading to conditions like atherosclerosis.1

Ready to start?

Answer a few questions and take your first step to living well.
Get Started

Have more questions?

We’re here to help you get where you need to be.
Talk to an Expert