Day 1
By delivering NAD+ through the nose-to-brain pathway, intranasal may support focus and mental clarity within the first day of use.5 6
Cognitive Function
Mood Support
NAD+ Nasal Spray Rx
Support mental clarity, focus, and cognitive energy with an easy, injection-free way to boost NAD+, designed to support brain pathways and sharper thinking on the go.
89% reported benefits by 2nd check-in
Supports brain NAD+ levels through targeted intranasal delivery⁶
Fast, convenient support for focus and mental clarity¹ ⁵
HSA / FSA eligible
Ongoing, expert support
Free, discreet shipping
100% online
Frequently asked questions
How does NAD+ Nasal Spray work?
NAD+ Nasal Spray delivers NAD+ (nicotinamide adenine dinucleotide) intranasally, allowing the coenzyme to bypass the digestive system and absorb directly through the nasal mucosa into the bloodstream.5 6 This delivery method may help support more direct cellular uptake compared to oral supplements, which require conversion and may vary in absorption between individuals.7
What is NAD+ Nasal Spray used for?
NAD+ Nasal Spray may help support cellular energy metabolism, focus, and mental clarity.1 2 Because intranasal delivery may allow NAD+ to be absorbed directly into the bloodstream, it may support brain energy and cognitive function as part of a broader longevity or wellness protocol.1 3
What is the difference between NAD+ Nasal Spray and NAD+ Injections?
Both NAD+ Nasal Spray and NAD+ Injections bypass the digestive system to potentially support more direct cellular absorption, but through different delivery mechanisms. Injections deliver NAD+ directly into the bloodstream via subcutaneous administration to support cellular energy and recovery.8 Nasal Spray delivers NAD+ intranasally through the nasal mucosa, which may help support focus and mental clarity.1 5
Usage instructions
View all FAQs
You can use NAD+ Nasal Spray 1-2x daily or as needed. If prescribed, a US-licensed provider will provide a tailored dosage schedule and specific treatment instructions with your care plan.
Important safety information and common side effects
Side effects
Side effects are generally mild in nature. Possible side effects include fatigue, headaches, or stomach discomfort.
If side effects occur, reduce use or discontinue use entirely.
Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Disclaimer
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality.
How NAD+ supports brain health
(nicotinamide adenine dinucleotide)Every thought, memory, and moment of focus requires cellular energy. NAD+ is the coenzyme that powers that process, but levels naturally decline with age, reducing the brain’s ability to produce energy and repair cellular damage.3 4 6
Supporting healthy NAD+ levels may help keep the mind as sharp as your ambitions.3 4
Brain NAD+ levels decline up to 25% between age 20 and 60.⁹
25%
How NAD+ Intranasal Spray works
30 Days
With consistent use, some report clearer thinking, improved focus, and more stable mental energy throughout the day.2
3 Months
As NAD+ levels stabilize, some notice better mental stamina and recovery from stress.1 0
6 Months
Maintaining NAD+ levels may support brain metabolism and energy production to promote learning, processing speed, and memory.1 2 4
1 Year and Beyond
Studies suggest continued NAD+ support may have neuroprotective effects by clearing brain plaque and supporting neuroplasticity for long-term brain health.3 4 1 1
Day 1
By delivering NAD+ through the nose-to-brain pathway, intranasal may support focus and mental clarity within the first day of use.5 6
30 Days
With consistent use, some report clearer thinking, improved focus, and more stable mental energy throughout the day.2
3 Months
As NAD+ levels stabilize, some notice better mental stamina and recovery from stress.1 0
6 Months
Maintaining NAD+ levels may support brain metabolism and energy production to promote learning, processing speed, and memory.1 2 4
1 Year and Beyond
Studies suggest continued NAD+ support may have neuroprotective effects by clearing brain plaque and supporting neuroplasticity for long-term brain health.3 4 1 1
Results you can feel
- 0
- felt benefits by 2nd check-in
- 0
- felt more energized
- 0
- reported better mental clarity
- 0
- felt cognitive benefits
Actual results may vary. Data was self reported by 131 surveyed customers who checked in with their provider between first and third check-in between 4/18/22 and 10/28/25. All respondents are AgelessRx NAD+ Nasal Spray customers who were approved for a prescription after completing an assessment with a medical provider.
We’re global leaders in NAD+ research
With 70,000+ NAD+ users supported and multiple peer-reviewed clinical trials, our in-house Stanford PhD-led Research Team is setting the benchmark for research-driven, clinician-guided NAD+ protocols.
Built on one of the largest real-world NAD+ datasets in longevity care
Studied by our Stanford PhD–led Research Team in the $101M XPRIZE Healthspan competition
Prescription-grade ingredients compounded by LegitScript-certified pharmacies
Clinically studied
The science of NAD+
NAD+ is a critical molecule that is essential for cellular functions—including energy production, DNA repair, inflammation control, and circadian rhythm. But our natural NAD+ levels decline with age, impacting our skin health, energy levels, and risk of age-related disease.1 2
Low NAD+ levels are linked to fatigue, insulin resistance, frailty, and neurodegenerative disorders like Alzheimer’s. But studies show that restoring NAD+ levels may promote healthy aging and enhance overall quality of life.1 3
How it works
Choosing how you age starts here
1
Clinician-led
Connect with a clinician
Connect with a US-licensed medical provider to ensure your treatment is right for you. 100% online. No in-person visit required.
2
Fast, discreet shipping
Get your discreet shipment
Once approved, your prescription is fulfilled by a U.S.-licensed, certified pharmacy partner and rigorously inspected for quality in 5 days or less.
3
100% online
Receive continuous support
Easy refills and direct updates from your provider are just the start. Connect with our team to get personalized support, anytime.
Disclaimer
The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Products are compounded by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. See above for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.
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Frequently asked questions
Individual experiences vary. Some people may begin noticing initial changes with consistent use, while others may find that effects become more noticeable over several weeks as NAD+ levels build over time.⁸ ¹⁰
NAD+ Nasal Spray is generally well tolerated. The most commonly reported side effects are mild and may include a slight burning or stinging sensation upon administration, nasal irritation, or temporary congestion. Side effects typically resolve on their own. As with any prescription treatment, please see important safety information and consult your provider about the potential risks and benefits before use.
NAD+ Nasal Spray may be used 1–2 times daily or as directed by your prescribing provider. Your AgelessRx provider will guide your dosing schedule based on your individual health history and goals.
Refrigeration is recommended. Keeping your NAD+ Nasal Spray refrigerated may help preserve the integrity of the solution. Do not freeze. Keep out of direct light and out of reach of children. Follow any additional storage instructions included with your prescription.
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