What NAD+ may support
Available as clinician-guided injections, patches, nasal spray, and face cream.
How NAD+ works
NAD+ fuels mitochondrial energy production, switching on sirtuins (genes for stress-resistance and repair), and supplying the enzymes that fix damaged DNA. It’s the shared currency behind all three, which is why one molecule touches so much.1
NAD+ levels drop up to 90% from age 30 to 60.2
NAD+ longevity benefits
What we still don’t know
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NAD+ Injection
Boost energy, improve focus, and support cellular health with one of the most effective methods of restoring depleted NAD+ levels for a fraction of the cost of IV infusions.
NAD+ Nasal Spray
Support mental clarity, focus, and cognitive energy with an easy, injection-free way to boost NAD+, designed to support brain pathways and sharper thinking on the go.
NAD+ Patches
Support steady energy, endurance, and recovery with an easy, injection-free way to boost NAD+ for lasting cellular energy.
NAD+ Face Cream
Supports smoother, brighter, firmer-looking skin with a clinician-guided formula that delivers pure NAD+ to address visible signs of aging.
Frequently asked questions
AgelessRx offers NAD+ as an Injection, Nasal Spray, Patch, and Face Cream because each reaches the body differently.
Injections and patches deliver NAD+ directly, bypassing some of the gut and liver metabolism that limits how much oral precursors like NMN or NR absorb. The nasal spray is designed to reach the brain more directly, and a clinician helps match the format to your goals.
Oral precursors are broken down by liver metabolism before reaching the bloodstream, limiting how much reaches cells intact. Direct-delivery formats bypass more of that first-pass loss.
Our prescription formats are built around this research. The field is still mapping how much of each format reaches target tissue, and we would rather be transparent about that than overstate it.
There is no single at-home test that confirms cellular NAD+ levels are rising. Most people and their care team track self-reported changes in energy, focus, and recovery over several weeks, plus standard bloodwork a clinician already follows.
Blood NAD+ testing exists in research settings but is not yet a validated individual-level tool.
NAD+ is generally suited to adults already caring for themselves through diet, sleep, and exercise who want extra support for energy, focus, or recovery.
It is not a treatment for a diagnosed condition and is not appropriate during pregnancy or breastfeeding without clinician guidance. A clinician reviews your health history first.
Dosing starts conservatively and is adjusted based on how you respond, guided by ranges used in published human research. The goal is the lowest effective amount for your format and goals.
NMN and NR are precursors the body converts into NAD+ through additional steps. Our formats deliver NAD+ more directly, reducing reliance on how efficiently a person converts an oral precursor.
Some evidence suggests direct delivery may also engage cellular signaling that precursors do not access the same way, though this is still being studied. This page notes which studies used which.
NAD+ status depends on your own baseline metabolism—how efficiently your body makes, recycles, and uses it—which is shaped by inflammation, mitochondrial health, and other individual factors.
People who are more depleted to start with often notice more than those with less room to improve. This is why we track your own markers over time rather than chasing a universal target.