Heart disease can build silently for years, but many of its major risk factors can be managed early. This once-daily statin helps lower cholesterol linked to plaque buildup to reduce the risk of heart attack and stroke.
Starting at$30/ mo
Telmisartan
Support healthier blood pressure and long-term heart health with an FDA-approved treatment with emerging potential to support cardiometabolic health and inflammation for the years ahead.
Starting at$30/ mo
Tadalafil
Support stronger, longer-lasting erections for up to 36 hours with the same active ingredient in Cialis®, so intimacy can fit your life instead of the other way around.
Starting at$45/ mo
Tadalafil for Longevity
One low daily dose for both men and women that may help blood vessels stay relaxed and responsive, supporting circulation to the heart, brain, muscles, and organs for years to come.
Starting at$60/ mo
Glutathione Injection
Support energy, immunity, cellular detox, and healthy skin by helping replenish the body’s master antioxidant that naturally declines with age.
Starting at$99/ mo
Microdosing Semaglutide
A low dose GLP-1 approach designed to work in sync with your body, which may support moderate weight loss and cravings while minimizing side effects.
Starting at$99/ mo
Five levers. One complete plan.
Heart health is shaped by connected systems—not a single number. See how each lever contributes to the bigger picture.
Cholesterol
Atorvastatin helps lower LDL and ApoB, potentially reducing the number of plaque-forming particles circulating in your bloodstream.
Blood pressure
Telmisartan helps relax blood vessels and may reduce the pressure your heart and arteries carry every day.
Circulation
Tadalafil supports blood flow and vascular responsiveness, helping circulation reach the organs and tissues that depend on it.
Oxidative stress
Glutathione supports antioxidant defenses that may help protect cells and blood vessels from oxidative stress over time.
Metabolic health
Microdosing GLP-1 or an SGLT2 Inhibitor may support glucose regulation and other metabolic factors connected to cardiovascular risk.
Cholesterol
Atorvastatin helps lower LDL and ApoB, potentially reducing the number of plaque-forming particles circulating in your bloodstream.
Blood pressure
Telmisartan helps relax blood vessels and may reduce the pressure your heart and arteries carry every day.
Circulation
Tadalafil supports blood flow and vascular responsiveness, helping circulation reach the organs and tissues that depend on it.
Oxidative stress
Glutathione supports antioxidant defenses that may help protect cells and blood vessels from oxidative stress over time.
Metabolic health
Microdosing GLP-1 or an SGLT2 Inhibitor may support glucose regulation and other metabolic factors connected to cardiovascular risk.
Heart health is built over years
Heart risk takes shape over years, not overnight. Supporting cholesterol, blood pressure, circulation, oxidative stress, and metabolic health earlier may help reduce the strain that builds over time.2 3
lower heart event rate associated with Tadalafil1 5
Disclaimer
Actual results may vary. Data was self-reported by 73 surveyed Atorvastatin customers and 371 Telmisartan customers who checked in with their provider on their second check-in between 4/11/22-2/5/26. All respondents are AgelessRx customers who were approved for a prescription after completing an assessment with a medical provider.
Support your heart from every angle
Heart risk is rarely driven by one thing. See how different care options may support each part of your heart health plan.
Lever
Supported by
Cholesterol
Atorvastatin supports LDL, ApoB, and plaque exposure
Blood pressure
Telmisartan supports pressure control and vascular strain
Circulation
Tadalafil supports blood flow and vascular responsiveness
*The above chart is not meant for medical diagnosis purposes. Your provider will approve or disapprove a prescription at their discretion after careful consideration of your unique health profile; approval is not guaranteed based on the above criteria.
Heart protection that builds over time
2 Weeks
Blood pressure and cholesterol may begin improving as Telmisartan relaxes blood vessels and Atorvastatin reduces cholesterol production.4 5
30 Days
Atorvastatin may approach its near-full effect, leaving fewer LDL and ApoB particles circulating with the potential to enter artery walls.6
3 Months
Labs may reveal meaningful reductions in heart disease risk with changes in LDL and ApoB, while home readings may show blood pressure stabilizing.7 8
6 Months
More time in healthier ranges may mean less cumulative exposure to plaque-forming particles, elevated blood pressure, and cardiac-driven stress that shape long-term risk.9
1 Year and Beyond
Protection compounds. Every 39 mg/dL reduction in LDL showed 20% fewer major heart events, while better blood pressure has reduced cardiovascular risk by 20%–25% in major trials.10 11
2 Weeks
Blood pressure and cholesterol may begin improving as Telmisartan relaxes blood vessels and Atorvastatin reduces cholesterol production.4 5
30 Days
Atorvastatin may approach its near-full effect, leaving fewer LDL and ApoB particles circulating with the potential to enter artery walls.6
3 Months
Labs may reveal meaningful reductions in heart disease risk with changes in LDL and ApoB, while home readings may show blood pressure stabilizing.7 8
6 Months
More time in healthier ranges may mean less cumulative exposure to plaque-forming particles, elevated blood pressure, and cardiac-driven stress that shape long-term risk.9
1 Year and Beyond
Protection compounds. Every 39 mg/dL reduction in LDL showed 20% fewer major heart events, while better blood pressure has reduced cardiovascular risk by 20%–25% in major trials.10 11
Disclaimer
The above statements have not been evaluated by the Food and Drug Administration. These product(s) are not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. Compounded products are compounded by a licensed pharmacy. Generic products are fulfilled by a licensed pharmacy. The FDA has not reviewed or approved compounded products for any use for safety, efficacy, or quality. See above for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.
Three science-backed levers for better heart health
Telmisartan
Starting at $30/mo
Atorvastatin
Starting at $30/mo
Tadalafil for Longevity
Starting at $60/mo
Delivery
Pill
Pill
Pill
Frequency
Once daily
Once daily
Once daily
Benefits
Helps reduce pressure carried by the heart⁸
Helps limit particles that contribute to plaque over time⁶
Helps blood flow reach the heart, brain, and organs¹²
Heart prevention backed by a Stanford PhD-led team
Our Stanford PhD-led Research Team turns the latest prevention science into care you can act on—helping you understand which risks matter and where your plan may begin.
AgelessRx is the same company that I use for the multi-cancer early detection test
Helen
AgelessRx has truly been one of the best healthcare experiences I’ve had. Their patient care is unmatched, responsive, supportive, and genuinely caring. Highly recommend to anyone looking to invest in their long-term health and wellness!
Zainab
I highly recommend AgelessRx to anyone looking to improve their overall health and quality of life.
Verified customer
Natalie
They are pleasant to work with. You can openly talk with your provider when concerns arise. The shipments arrive fast. What else can I say allow them to help you reach your goals of longevity and improved health and wellbeing.
Shanta
The emphasis on helping me achieve optimum health is a fresh contrast to established medical practices of treating symptoms, instead of targeting root causes. Thank you for improving my longevity and the quality of my years.
Karina
The medical and support Team at AgelessRx is outstanding. If you are looking for a longevity and health science team that knows much more than most doctors. This is the place for you. I highly recommend them!
Geoffrey
AgelessRx is the same company that I use for the multi-cancer early detection test
Helen
AgelessRx has truly been one of the best healthcare experiences I’ve had. Their patient care is unmatched, responsive, supportive, and genuinely caring. Highly recommend to anyone looking to invest in their long-term health and wellness!
Zainab
I highly recommend AgelessRx to anyone looking to improve their overall health and quality of life.
Verified customer
Natalie
They are pleasant to work with. You can openly talk with your provider when concerns arise. The shipments arrive fast. What else can I say allow them to help you reach your goals of longevity and improved health and wellbeing.
Shanta
The emphasis on helping me achieve optimum health is a fresh contrast to established medical practices of treating symptoms, instead of targeting root causes. Thank you for improving my longevity and the quality of my years.
Karina
The medical and support Team at AgelessRx is outstanding. If you are looking for a longevity and health science team that knows much more than most doctors. This is the place for you. I highly recommend them!
Geoffrey
Videos feature both paid actors and actual users, however all results and/or effects are reflective of real customer experiences. Individual results may vary.
You only have one heart
You can eat well, exercise, and still carry risk from age, genetics, cholesterol, or blood pressure.13
The right support may add another layer of protection—helping your healthy choices go further for the life you’ve worked so hard to build.
Heart prevention should not require months of waiting or piecing together disconnected advice. Get evidence-backed care personalized to your health, with ongoing support as your needs change.
Pick which lever you want to prioritize first. Then, answer a few key questions so an in-house provider can review your health history, concerns, and heart-health goals.
Your body’s clock is running 6 years younger than your chronological age.
Heart health educational content medically reviewed by our experts
Dr. Jenell Decker, MD
Medical Director
Trusted expert in preventative care, integrative medicine, and longevity driven clinical practice.
Marshall University Joan C. Edwards School of Medicine
East Carolina University
Concord University
Frequently asked questions
01How can I check my heart health at home?
A validated upper-arm blood pressure monitor is one of the most useful tools you can have on hand, checked weekly, ideally after sitting quietly for a few minutes with your feet flat on the floor.
Tracking your resting heart rate, generally 60 to 100 beats per minute for most adults, gives you another simple data point, either by checking your pulse manually or through a fitness tracker.
Many smartwatches now include FDA-cleared single-lead ECG features that can flag irregular rhythms like atrial fibrillation for a provider to review.
None of these replace a full lab panel or a conversation with your provider, but together they give you a useful, ongoing picture between checkups. For a deeper look at what’s happening beneath the surface, AgelessRx’s Core Longevity Panel adds bloodwork markers like ApoB that home monitoring can’t capture.
02What supplements are good for heart health?
Omega-3s (EPA and DHA) have some of the deepest research behind them, with higher intake linked to better blood pressure, lower inflammation markers, and healthier triglyceride levels. CoQ10 supports the mitochondria inside heart muscle cells and is worth particular attention if you’re on a statin like Atorvastatin, since statins can lower the body’s natural CoQ10 levels. Fiber and magnesium also show up consistently in the research, fiber for supporting healthy cholesterol levels, and magnesium for its role in blood pressure and heart rhythm.
Supplements can be a genuinely useful piece of the picture, but they work alongside your treatment plan, not in place of it, so it’s worth running anything new by your provider first, especially if you’re already on a heart health prescription.
03How to maintain heart health long-term?
The fundamentals do most of the work: regular movement, aiming for about 150 minutes of moderate activity a week, a diet built around vegetables, fiber, and healthy fats, not smoking, and keeping stress in check where you can.
Beyond lifestyle, staying on top of your numbers—blood pressure, cholesterol, and inflammation markers—lets you and your provider catch shifts early rather than after symptoms show up. For some people, that also means an ongoing prescription like Atorvastatin or Telmisartan alongside those habits, not instead of them. Think of it less as a single change and more as a handful of small, consistent habits that compound over years.
04What's the difference between Atorvastatin, Telmisartan, and Tadalafil, and how do I know which one I need?
Each works on a different piece of cardiovascular health. Atorvastatin supports healthy cholesterol levels, Telmisartan supports healthy blood pressure, and Tadalafil supports blood flow and circulation, with ongoing research also pointing to broader cardiovascular benefits from consistent daily use.
Many people end up using more than one, since blood pressure, cholesterol, and circulation are separate systems that don’t necessarily move together. Your provider reviews your labs and health history to help determine which one, or which combination, actually fits your profile.
05When do I need to start thinking about heart health?
Cardiovascular risk factors like blood pressure and cholesterol can begin shifting well before you’d notice any symptoms, often starting in your 30s and 40s. Rather than waiting for a specific age or a diagnosis, many people in the longevity space start monitoring these markers proactively, so small changes get caught early instead of compounding for years. Your AgelessRx provider can help you figure out what monitoring makes sense based on your personal and family history, whatever your current age.
PubMed is where the heart is.
We vet everything on PubMed so you don’t have to. Here’s what the science says.
1
This NIH resource outlines key numerical benchmarks (blood pressure, cholesterol, blood sugar, BMI) that indicate cardiovascular health for the general public.
2
This review highlights that atherosclerosis and cardiovascular events are increasingly common in younger adults (20-40 years).
3
This CDC resource summarizes evidence-based strategies for preventing heart disease, including managing blood pressure, cholesterol, and lifestyle risk factors.
4
This review argues that apolipoprotein B is a better marker of cardiovascular risk than LDL cholesterol alone and statins lower both effectively.
5
This review explains that Telmisartan’s 24-hour half-life gives it superior blood pressure control compared to shorter-acting antihypertensives like ramipril and valsartan.
6
This clinical reference summarizes Atorvastatin’s pharmacology, dosing, indications, and safety monitoring for practitioners.
7
This 6-week dose-ranging trial found Atorvastatin produced dose-dependent LDL cholesterol reductions of 25–61% in patients with primary hypercholesterolemia.
8
This review highlights Telmisartan as the first ARB shown to reduce cardiovascular risk in high-risk patients, based on results from the landmark ONTARGET and TRANSCEND trials.
9
This review summarizes Atorvastatin’s extensively studied benefits in both primary prevention and secondary prevention of cardiovascular events.
10
This study found that tailoring statin treatment to baseline LDL cholesterol may optimize cardiovascular benefit compared to an LDL reduction strategy alone.
11
This review argues that blood pressure lowering alone only reduces cardiovascular risk by 20–25%, and that achieving truly optimal risk reduction requires adding statin therapy to address lipids and hypertension.
12
This review explores Tadalafil’s potential cardiovascular benefits including improved endothelial function and possible protective effects against adverse heart events.
13
This review examines how pharmacological treatment and lifestyle changes each independently reduce cardiovascular risk, concluding that combining both approaches produces the most synergistic benefit.
14
This comprehensive review proposes a new framework of twelve hallmarks of cardiovascular aging including metabolic dysfunction, inflammation, and oxidative stress.
15
This retrospective cohort study of 8,156 Tadalafil users versus 21,012 non-users with erectile dysfunction found a 44% lower all-cause mortality rate and 19% lower major cardiovascular event rate overall, with a 60% lower MACE rate in the highest- vs. lowest-exposure quartile.