RAPAMYCIN PROTOCOL
A limited opportunity for those who qualify to explore the potential health benefits of Rapamycin.
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How to Get Started
Explore Potential Protocols†
- Generic Rapamycin (Sirolimus tablets)
- Compounded Rapamycin (capsules)
- Both protocols taken once weekly
- Both require a doctor-guided, monthly titration process
- Each all-in-one protocol includes visit, prescription, medication & ongoing labs
Complete Pre-Screening
- Explore protocol options with a physician†
- Complete a free online medical visit*
- Complete baseline blood work‡
- If approved, receive medication from a certified, US-based pharmacy*
Maintain Ongoing Monitoring & Reporting
- Steadily titrate to your ideal dose according to your prescriber
- Regularly report any benefits or side effects you detect
- Fill out periodic questionnaires
- Follow required blood work schedule‡
Curious If You Qualify?
Complete Your Free Visit Now.
- Generic Sirolimus tablets
- Guided weekly titration, as determined by prescriber*
- Taken once weekly
- Sourced from a certified US-based pharmacy
- Prescription, blood draws & medication included‡
Code RAPA50: $50 off for life & FREE medical evaluation
- Compounded capsules
- Guided monthly titration, as determined by prescriber*
- Taken once weekly
- Sourced by a certified US-based pharmacy
- Prescription, blood draws & medication included‡
Currently unavailable in AL, AR, KY, LA, MS, NC, ND, NY, NJ, RI & SC.
If approved, you are indicating an interest in enrolling in an IRB-approved observational trial
You must adhere to the required lab schedule to receive refills
You may pause or cancel at any time
*Prescription products require evaluation with a licensed medical professional who will determine if a prescription is appropriate. Not all who apply will be eligible. See below for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Medication is only prescribed if enrolled in the protocol. Actual product packaging may appear differently than shown.
FAQs
What dose will I receive?
Your dosage will depend on whether you are approved for the generic or the compounded protocol. You can only receive medication following a medical review and initial screening.
The generic (Sirolimus) protocol is a titrated plan to move from 2mg to 6mg per week over three months, ultimately ending at 6-8mg (at the discretion of the prescriber).
The compounded protocol is a titrated plan to move from 5mg to 10mg per week over three months, ultimately ending at 10-15mg (at the discretion of the prescriber).
How often do I take Rapamycin?
If, after doctor review and screening, you are selected as a candidate for the AgelessRx Rapamycin Beta Protocol, you will only take one dose of Rapamycin each week. You may take more than one pill as part of your titration plan, but the frequency will not change. For example, if you receive 2mg pills and your dose is currently 8mg, then you will take four pills in a single day (rather than four pills spread over the week) and be done until the next week.
Who is eligible to enroll?
If, after doctor review and screening, you are selected as a candidate for the AgelessRx Rapamycin Beta Protocol, you must be at least 40 years of age, clinically stable, and in relatively good health (all of which will be assessed during your initial and ongoing visits) to take Rapamycin. You must also be able to give informed consent of your willingness to take off-label Rapamycin and to undergo routine bloodwork, as well as technologically capable to join virtual meetings and fill out online forms. There are no limitations on sex or ethnicity, and no maximum age limit.
What is the difference between the generic and compounded Rapamycin protocols?
The generic protocol contains Sirolimus tablets that are commercially available, whereas the compounded protocol contains capsules mixed by a certified compounding pharmacy.
AgelessRx possesses data to show that compounded Rapamycin is absorbed, however, it may be absorbed at a different rate than commercially available generic Sirolimus. By exactly what ratio and under what conditions we are uncertain. We are actively investigating this and will make it public once we’re certain of a conclusion. Regardless, we are confident in the quality of both products and are excited to bring affordable Rapamycin to the AgelessRx community.
See All FAQsIMPORTANT SAFETY INFORMATION &
COMMON SIDE EFFECTS
The protocols outlined on this page are exclusive to the AgelessRx Beta Rapamycin Protocol, an observational, real-world evidence trial. All details related to these protocols are subject to change when the trial population is full or when the trial has concluded. Not all who enroll will be eligible to participate.
By electing to enroll and complete a free visit, you have the opportunity to consult with an AgelessRx prescriber about your health, medical history, and lifestyle. Your prescriber will use this information to evaluate your overall health and, if appropriate, prescribe medication in tandem with monitoring as part of the protocol.
Most Common Rapamycin Side Effects
Rapamycin is generally a well-tolerated medication and most often exhibits the following minor side effects:
- Mouth ulcers (stomatitis)
- Nausea
- Diarrhea
For a full list of possible side effects, click here.
Other Important Safety Information
As a substrate for p-glycoprotein and cytochrome P-450 3A4, Rapamycin may have certain interactions with other drugs or supplements that act on these proteins. These include cyclosporine, rifampin, ketoconazole, cidofovir, ritonavir, mifepristone, posaconazole, fluconazole, and grapefruit juice.
Before taking Rapamycin, be sure to review the full list of potential drug interactions and talk to your healthcare provider about any medications you are currently taking.
Do not take Rapamycin if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. Do not take Rapamycin if you are scheduled to undergo major surgery, chemotherapy or immunosuppressant therapy for a transplant within the next 6 months; have a chronic infection (such as HIV/AIDS, Lyme disease, etc.), have any primary or secondary immune dysfunction or deficiency, and/or any allergy to Rapamycin or any of its ingredients.
While rare, it is possible that some who take Rapamycin may potentially become more susceptible to skin and/or lung infections. However, this is still being investigated and is not a proven risk associated with Rapamycin when taken at the frequency and doses prescribed at AgelessRx. If, at any time, you feel you are developing a troubling skin or lung infection, seek care at a local urgent care center, contact your PCP, or use an acute-care telemedicine service as soon as possible. Be sure to report the details to our medical team when you are able.
Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
† The protocols outlined on this page are exclusive to the AgelessRx Beta Rapamycin Protocol, an observational, real-world evidence trial. All details related to these protocols are subject to change when the trial population is full or when the trial has concluded.
‡ Please be advised that failure to participate in the initial or ongoing reporting requirements (including labs and questionnaires) will result in immediate termination of your eligibility to participate in this protocol and/or suspension of treatment.