Brain
Healthy circulation supports oxygen and nutrient delivery.
New
Longevity
Tadalafil Longevity Gummy Rx
The first-ever Tadalafil gummy for longevity—for both men and women. A low daily dose with Vitamin D3 that supports healthy blood flow to the heart, brain, and muscles.
Supports healthy blood flow throughout the body for men + women¹
Vitamin D3 to support muscle, immune + cardiovascular health⁸
Lemon lime flavor with 2.5mg low-dose Tadalafil + Vitamin D3
Quarterly plan billed in full upfront
Free, discreet shipping
Ongoing, expert support
Pause or cancel anytime
Frequently asked questions
Why are Vitamin D3 and Tadalafil combined?
Vitamin D3 plays a foundational role in bone health, immune function, and calcium balance, and Vitamin D receptors are also found throughout vascular tissue.9 Each gummy includes 600 IU as everyday nutritional support alongside low-dose Tadalafil. Two levers on aging biology, not one ingredient doing double duty.
Why take Tadalafil every day?
Tadalafil is long-acting, which makes it especially well-suited to daily use. With consistent dosing, levels build over several days and remain steady, providing continuous support for healthy blood-vessel relaxation rather than a short-lived peak. AgelessRx offers Tadalafil for Longevity in both gummy form and as a daily pill.
Can both men and women take the Tadalafil Longevity Gummy?
Yes. Eligible men and women may be prescribed low-dose Tadalafil for longevity. Eligible women can take low-dose Tadalafil when prescribed off-label by a licensed provider. This isn’t a men’s-only mechanism: PDE5 inhibition works through the same nitric oxide–cGMP pathway in both sexes, and it’s already an approved, effective therapy for pulmonary hypertension in women.4
In a 3-month randomized, placebo-controlled trial of 96 women with overactive bladder, daily low-dose Tadalafil (5mg) significantly reduced urinary frequency, urgency, and incontinence episodes compared to placebo, with improvements sustained through 3 months post-treatment.5 Another recent trial found improvements in sexual function and clitoral blood-flow measures in a specific female population.7
Beyond cardiovascular associations, daily low-dose Tadalafil has its own dedicated placebo-controlled study in which 96 women found significant improvement in overactive bladder symptoms over 3 months. Real, women-specific RCT evidence for the daily-dosing approach, not just an extrapolation from male cardiovascular data.5 Evidence for female longevity specifically is still emerging, so treatment should be personalized.
What ingredients does the Tadalafil Longevity Gummy contain?
The Tadalafil 2.5mg Vitamin D3 600 IU Longevity Gummy comes in Lemon Lime flavor and contains the following ingredients:
Active Ingredients
-
- Tadalafil 2.5mg
- Vitamin D3 600 IU
Inactive Ingredients
-
- Citrus Pectin
- Sucrose
- Corn Syrup
- Purified Water
- Sodium Citrate
- Citric Acid
- Lemon Lime Flavor
- Yellow Color
- Carnauba Wax
Usage instructions
View all FAQs
Take one gummy daily by mouth according to your provider-guided dosing plan. Each gummy contains 2.5mg Tadalafil + 600 IU Vitamin D3. If prescribed, a US-licensed medical provider will provide a tailored dosage schedule and specific treatment instructions with your care plan.
Important safety information and common side effects
Generally, people who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours. Daily Tadalafil use is usually associated with lower incidence and severity of side effects compared to as-needed Tadalafil dosing.
Most common Tadalafil side effects include headache, indigestion, back and/or muscle pain, flushing, and stuffy nose. Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:
- An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
- Sudden vision loss in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION).
- Sudden hearing decrease or hearing loss. Some may also have ringing in the ears (tinnitus) or dizziness.
For a complete list of possible side effects, please review Mayo Clinic’s Tadalafil resources.
Possible drug interactions
Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.
For a complete list of possible drug interactions, please review Drugs.com’s Tadalafil resource.
Other important safety information
Those who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may experience side effects such as fainting or light-headedness. Because those with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heartbeats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these users. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Users should seek prompt medical attention if their erection lasts longer than four hours.
After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if people have problems with their kidneys or liver, or they are taking certain other medications.
Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Disclaimer
Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate.
Why we made the first-ever Tadalafil longevity gummy
Your heart. Your brain. Your muscles. They all depend on blood flow bringing oxygen and nutrients where your body needs them most.
So we made a gummy for both men and women: low-dose Tadalafil to support healthy blood flow, plus Vitamin D3 for muscle, immune, and heart health.
Clinician-guided for men and women
One pathway. Whole-body impact.
You know Tadalafil for ED, but healthy blood flow reaches a lot further than the bedroom.
Heart
Responsive blood vessels support cardiovascular function.
Muscles
Blood flow helps deliver the oxygen and nutrients muscles need to perform.
Whole body
Healthy circulation supports tissues and organs from head to toe.
Brain
Healthy circulation supports oxygen and nutrient delivery.
Heart
Responsive blood vessels support cardiovascular function.
Muscles
Blood flow helps deliver the oxygen and nutrients muscles need to perform.
Whole body
Healthy circulation supports tissues and organs from head to toe.
What research shows about low dose Tadalafil
- 0
- fewer major cardiovascular events²
- 0
- lower risk of all-cause mortality²
- 0
- lower risk of Alzheimer's disease³
How Tadalafil Longevity Gummy works over time
2 Weeks
Daily Tadalafil reaches steady levels, supporting consistent nitric oxide–cGMP signaling and healthy blood flow.
30 Days
Continued PDE5 inhibition may support endothelial function, helping blood vessels stay relaxed and responsive.
3 Months
Consistent vascular support may promote healthier circulation, exercise capacity, and cardiovascular function.
6 Months
Longer-term PDE5 support may benefit vascular and metabolic health as research into healthy aging continues.
1 Year and Beyond
Long-term PDE5 inhibitor use has been associated with fewer heart attacks and lower risk of Alzheimer’s and all-cause mortality in large observational studies.2 6
2 Weeks
Daily Tadalafil reaches steady levels, supporting consistent nitric oxide–cGMP signaling and healthy blood flow.
30 Days
Continued PDE5 inhibition may support endothelial function, helping blood vessels stay relaxed and responsive.
3 Months
Consistent vascular support may promote healthier circulation, exercise capacity, and cardiovascular function.
6 Months
Longer-term PDE5 support may benefit vascular and metabolic health as research into healthy aging continues.
1 Year and Beyond
Long-term PDE5 inhibitor use has been associated with fewer heart attacks and lower risk of Alzheimer’s and all-cause mortality in large observational studies.2 6
We’re leading experts in Tadalafil
Our Stanford PhD-led Research Team follows emerging evidence around PDE5 inhibition, blood flow, and healthy aging—then works alongside our clinicians to translate promising science into responsible, personalized care.
100,000+ real-world health data points
Stanford PhD-led review of PDE5 and cGMP research
199+ years of combined clinical experience with personalized protocols
Clinically studied
The science of the Tadalafil Longevity Gummy
Tadalafil blocks PDE5, allowing cGMP to stay active longer, helping blood vessels remain relaxed and responsive and supporting healthy circulation throughout the body.
Vitamin D3 adds 600 IU of daily support, the Recommended Dietary Allowance for adults, supporting bone and immune health.8
One ingredient focuses on a promising vascular pathway, the other provides foundational nutritional support.
How it works
Choosing how you age starts here
1
Clinician-led
Connect with a clinician
Connect with one of our US-licensed, in-house medical providers with 199+ years of combined clinical experience to make sure treatment is right for you. 100% online. No in-person visit required.
2
Fast, discreet shipping
Get your discreet shipment
If approved, your treatment is fulfilled by a US-licensed, LegitScript-certified pharmacy partner, rigorously inspected for quality, and shipped discreetly to your door.
3
100% online
Receive continuous support
Start with one goal, then keep building over time. With our in-house care team, unlimited provider messaging, easy refills, unlimited dosage adjustments, and 40+ science-backed plans, your care evolves with you.
Get Started
Disclaimer
The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. See above for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.
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Frequently asked questions
More isn’t always better. We start with 2.5mg daily to provide consistent low-dose exposure while keeping the protocol personalized. If appropriate, your provider may increase your dose to 5mg daily based on your response and individual needs.
Tadalafil is long acting, which makes it well-suited to a daily routine. With consistent dosing, levels build over several days and reach a steady state, providing ongoing PDE5 inhibition rather than requiring you to time each dose.
Yes. Eligible men and women may be prescribed low-dose Tadalafil for longevity. The nitric oxide–cGMP pathway it supports exists in both sexes, although much of the long-term research on cardiovascular outcomes and longevity has been conducted in men.
Beyond cardiovascular associations, daily low-dose Tadalafil has its own dedicated placebo-controlled study in which 96 women found significant improvement in overactive bladder symptoms over 3 months. Real, women-specific RCT evidence for the daily-dosing approach, not just an extrapolation from male cardiovascular data.⁵ That’s a real gap in the field, and part of why personalized provider guidance matters here specifically.
Maybe, but this isn’t a product you necessarily “feel” working every day. Tadalafil begins affecting PDE5 and cGMP signaling after you take it, while consistent daily dosing provides ongoing support for healthy blood flow. Some people may notice changes related to circulation, exercise, or sexual function, while others may not notice an obvious day-to-day difference.
It can. Tadalafil is FDA-approved for erectile dysfunction at approved dosing, and the same nitric oxide–cGMP pathway involved in vascular health also plays an important role in sexual response. The difference here is the goal: this low-dose daily protocol is built around ongoing vascular support rather than timing a medication around sex. If you’re interested in Tadalafil for erectile dysfunction or sexual health, explore Tadalafil (As Needed).
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