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Tadalafil (As Needed)

  • Pill

A fast-acting and long-lasting erectile dysfunction medication. All you need is a single dose of Tadalafil 1-2 hours before those intimate moments for up to 36 hours of enduring potency.

Starting at $45

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Love more, age less

  • PDE5 inhibitor used to treat erectile dysfunction
  • Generic form of Cialis with the same active ingredient
  • One dose can remain effective for up to 36 hours
  • No loading dose required—a single tab is effective
  • Take 1-2 hours before sexual activity
See the Science


Background and history

  • FDA approved to treat ED
  • Inhibits PDE5 enzymes to produce and maintain an erection
  • Improves ejaculatory latency time (premature ejaculation or failure to ejaculate)
  • Preferred 3-to-1 by men for ED in several clinical studies
  • A recent study shows women favor partners taking Tadalafil (Cialis) over other ED meds
Tadalafil (As Needed) Background and History

What Tadalafil experts are saying

It has also been observed that even long-term couples have a clear liking for this medication. They mention that [Tadalafil] Cialis lets them be spontaneous and experimental to bring out an element of spice in their relationship. Therefore, it helps in keeping the flame alive—however old the relationship is.

Dr. James Elist, MD, FACSInfertility, Impotency & Sexual Dysfunction Specialist
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Monthly 5 doses
$50 / month billed monthly | shipped quarterly
  • Starting at $10/tab
  • Includes 5 tabs per month
  • 10 or 20mg daily dose, as prescribed
  • Discreet packaging
  • Free shipping

CODE TADALAFIL10$10 off first month & FREE medical evaluation

Best deal
Quarterly 15 doses
$45 / month billed $135 quarterly | shipped quarterly
  • Starting at $9/tab
  • Includes 15 tabs per quarter
  • 10 or 20mg daily dose, as prescribed
  • Discreet packaging
  • Free shipping

CODE TADALAFIL25$25 off first quarter & FREE medical evaluation

Not Available in SC & ND

Doctor may recommend a different dose during medical intake process

You can request daily dose adjustments between refills

You will be automatically billed & sent refills based on your plan

You can pause or cancel at any time before your next shipment

* Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. See below for important safety information. Benefits outlined on are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.

Learn more about Tadalafil (Daily) here.


How do I take Tadalafil?

You will take a single Tadalafil tablet (10mg or as prescribed) with a glass of water 1-2 hours before desired sexual activity. It can be taken at any time of day or night, with or without food.

What’s the difference between Tadalafil and Cialis?

Tadalafil is the active ingredient used in Cialis and is the generic equivalent. As clinically evidenced, Tadalafil is just as safe and effective as branded Cialis; it works for the same amount of time and delivers the same lasting effects.

What are the advantages of Tadalafil over other ED meds?

Unlike other ED medications, Tadalafil is often referred to as “the weekend pill” because a single dose can remain active for up to 36 hours (whereas others, such as Viagra, remain active for only a few hours). Tadalafil provides the opportunity for spontaneity.

Recent studies also name Tadalafil (Cialis) as the preferred ED treatment by men.

See all FAQs

Important safety information and common side effects

As with any drug product, there may be side effects. Generally, patients who experience side effects usually get them within 12 to 24 hours after taking Tadalafil. Side effects usually resolve on their own within 48 hours.

Most common Tadalafil side effects

  • Headache
  • Indigestion
  • Back pain
  • Muscle pain
  • Flushing
  • Stuffy nose

Some more serious side effects have been reported. While rare, it is important to stop taking Tadalafil and contact a doctor right away if any of the following occur:

  • An erection will not go away (priapism). If you have an erection that lasts longer than 4 hours, get medical help right away. If not treated right away, priapism can permanently damage the penis.
  • Sudden vision loss in one or both eyes. Sudden vision loss can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropath (NAION).
  • Sudden hearing decrease or hearing loss. Some may also have ringing in the eyes (tinnitus) or dizziness.

For a complete list of possible side effects, click here.

Possible drug interactions

Some drugs/medications may interact with Tadalafil. You should not take Tadalafil if you are taking nitrates (such as nitroglycerin tablets or patches) because the combination of these with Tadalafil could significantly lower blood pressure and lead to fainting or even death. Additionally, do not take Tadalafil if you are taking Cisapride, other ED medications (e.g. Viagra), Adcirca, or Riociguat. 

On your intake form, please be sure to provide AgelessRx with all medications, herbs, non-prescription drugs, or dietary supplements you use. Also be sure to report if you smoke, drink alcohol, or use illegal drugs, as some may interact with your medication.

For a complete list of possible drug interactions, click here.

Other important safety information

Patients who have a condition called “left ventricular outlet obstruction” from valvular problems or heart muscle enlargement may get side effects such as fainting or light-headedness. Because patients with recent heart attacks or stroke, heart pains (angina), heart failure, uncontrolled blood pressure or uncontrolled irregular heart beats, severe liver disease, and retinal eye problems have not been studied, Tadalafil (Cialis) is not recommended for these patients. There may be rare occurrences of priapism or painful, prolonged erections. This is a serious condition that requires immediate medical attention. Patients should seek prompt medical attention if their erection lasts longer than four hours.

After taking a single tablet, Tadalafil can remain in the body for up to two days. It can remain longer if patients have problems with their kidneys or liver, or they are taking certain other medications.

Note: All information included on this page is a summary. It may not cover all possible information. If you have questions about this medication, talk to a doctor, pharmacist, or health care provider.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.