NAD+ & Inflammation

NAD+ & Inflammation

A quick overview of what we’ll cover in this blog post:

  • NAD+ and its role in the body
  • The importance of inflammation and why too much can be harmful
  • How NAD+ could help alleviate excessive inflammation

Even though inflammation sounds like a scary word, it’s actually a very normal (and important) process that happens in our bodies. But when inflammation is chronic, or happens regularly over a long period of time, it can cause health problems. That’s why it’s important to keep inflammation from getting out of control. But how do you do that?

While a number of treatment options exist, NAD+ may work as an effective supplement to help keep inflammation balanced. Whether you’re familiar with NAD+ or just learning about it, we’ll break it down for you the ways NAD+ could help with inflammation in the body!

What Exactly Is NAD+?

Discovered in the early 1900s as a vital component of alcohol fermentation, NAD+ is a naturally occurring enzyme in the body that plays a lot of different roles. Its main role, though, is to help cells turn nutrients into energy so they can carry out vital tasks, such as metabolism and DNA repair. Recent research has shown that we have less NAD+ as we age, which could be a potential cause of many age-related illnesses—that just proves how important NAD+ is!

But despite NAD+’s vital role in the body, researchers are only just starting to scratch the surface on the potential benefits of NAD+ supplementation.

Why Is Too Much Inflammation Bad?

Inflammation is a very important biological function. It helps the immune system fight back and destroy cells infected by bacteria and viruses (that’s why we get sore throats when we’re sick, for example). Inflammation is also how the body heals itself (that’s why skin around a cut gets red). And sometimes, inflammation affects areas we can’t see, such as the gut (which can cause symptoms like diarrhea).

However, too much inflammation can be a problem and can lead to a number of health complications, including heart disease and arthritis. Some chronic conditions, such as arthritis, Alzheimer’s disease, or autoimmune conditions, are characterized by excessive and unhealthy levels of inflammation.

What’s NAD+’s Role in Inflammation?

You probably guessed it, but research has shown that NAD+ plays a key role in helping reduce inflammation. Here’s how.

The natural process of aging inevitably increases inflammation, which in turn reduces NAD+ levels. This happens because as we get older, some cells stop replicating due to DNA damage as a result of reduced NAD+ levels, but these cells die like they should. Instead, they release signals to the body that trigger inflammation, one of the body’s natural attempts to prevent the growth of cancer cells. Supplementing NAD+ could help with DNA repair and reduce the number of cells releasing these inflammatory signals.

For example, a recent study in mice also showed favorable results for using NAD+ to treat brain inflammation that causes Alzheimer’s disease.

What Forms of NAD+ Are Available?

There are many forms available for administering NAD+, though pills, patches, injections, and IVs are the main forms. They each have different levels of convenience and effectiveness, so it’s important to learn about your available options before making a choice. Check out some of the NAD+ products offered by AgelessRx to see if they may be right for you!

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


What causes inflammation?
Inflammation is most often caused by diet and lifestyle habits. Sugar, stress, smoking, and drinking alcohol can all cause a buildup of inflammation within our bodies. Environmental factors like pollution can also lead to increased inflammation. The good news is that most causes of inflammation are within our control – by changing what we eat, how often we exercise, and how well we sleep, we can easily keep inflammation in check. For factors that we can’t control, we can turn to solutions like Low Dose Naltrexone.

What diseases does inflammation cause?
Inflammation is linked to an overwhelming range of age-related diseases, including autoimmune diseases like rheumatoid arthritis, metabolic diseases such as diabetes, cardiovascular diseases like coronary heart disease, and even cancer.

Is inflammation a hallmark of aging?
Yes and no. The original 9 hallmarks of aging didn’t include inflammation, even though many longevity experts highlight inflammation as a major cause of age-related disease. Recently, new hallmarks of aging were proposed, expanding the original list from 9 to 14. This new list includes inflammation as a hallmark of aging, confirming what many experts already knew. The 9 hallmarks of aging are still the most widely accepted list of the biological factors that drive aging, but as research continues, we may soon see 15, 16, or even more hallmarks of aging added to the list.