PEARL TRIAL

“If Rapamycin mechanism of action does not slow down aging then everything we know about biology is wrong” Mikhail Blagosklonny PHD, MD

Overview

PEARL stands for the Participatory Evaluation of Aging with Rapamycin for Longevity. AgelessRx, in affiliation with the University of California, will soon launch this revolutionary, low-cost, and formalized scientific study to evaluate the safety and effectiveness of Rapamycin in healthy adults for longevity.

​PEARL is a double-blind, randomized, placebo-controlled trial. Notably, it is the first nationwide telemedicine trial and the first large-scale intervention trial on longevity.

Introduction to Rapamycin for Longevity

“The overwhelming evidence suggests that rapamycin is a universal anti-aging drug”

​Mikhail Blagosklonny PHD, MD Recent and comprehensive analysis why Rapamycin can be used to treat aging, Mikhail Blagosklonny

“For persons over 50, it it most the important drug in the world today”

Alan Green, MD Comprehensive Overview of Dr.Green’s Medical Practice and over 500 patients taking Rapamycin to prevent age-related diseases

“…Rapamycin is currently the most effective and reproducible pharmacological approach for directly targeting the aging process to increase life span…”

​Matt Kaeberlein, PHD Matt Kaeberlein paper arguing for a clinical trial of rapamycin in patients with Alzheimer’s

How PEARL Works

  • AgelessRx will enroll over 200-400 adults (50 years of age or older) for up to one year
  • Participants will be assigned to a specific dosage group or a placebo control group
  • Each participant will receive multiple tests throughout the trial valued at over $3,000
  • Ongoing doctor evaluation will be provided to each participant

Tests That Participants will get Include:

  • Most advanced Biological Age Testing (methylation clocks)
  • Microbiome Test
  • Dexa Body Composition Testing
  • GlyconAge Test
  • Blood Panels with over 40 blood markers
  • Others
Click to See If You Qualify

Rapamycin Registry

Already taking Rapamycin? Please consider joining the Rapamycin Registry.​

Click to Submit Your Interest

Many Thanks to Our Esteemed Supporters, Sponsors & Collaborators

Mikhail V. Blagosklonny, M.D., PhD

Mikhail V. Blagosklonny,
M.D., PhD

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James Watson, M.D.

James Watson,
M.D.

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Joshua Rosenthal, MScEd

Joshua Rosenthal,
MScEd

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Alan S Green, M.D.

Alan S Green,
M.D.

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Rapamycin Press

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Better Humans

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Life Extension Advocacy Foundation

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AgeCurve

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