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  • Pill

Explore the most promising longevity therapy today, with ongoing monitoring and blood work included with your prescription.

Starting at $150

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Maintain Ongoing Monitoring & Reporting

Get started with a free visit

to see if Rapamycin is right for you. Your prescriber will provide a prescription at their discretion, if appropriate.

Complete blood work

to establish baseline blood levels and determine your continued eligibility. Blood work is required as part of your prescription.

Complete Pre-Screening
Explore Available Protocols

Maintain ongoing monitoring

and regularly report any benefits or side effects you notice by filling out periodic questionnaires to see how far you’ve come!

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Generic Rapamycin
$150 / month billed $450 quarterly | free shipping
  • Generic Sirolimus tablets
  • Weekly, doctor-guided titration*
  • Taken once weekly
  • Sourced from a certified US-based pharmacy
  • Prescription includes required ongoing blood work

Currently unavailable in  NJ, NY, and RI.

You must adhere to the required lab schedule to receive refills

You may pause or cancel at any time

*Prescription products require evaluation with a licensed medical professional who will determine if a prescription is appropriate. Not all who apply will be eligible. See below for important safety information. Benefits outlined on are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Medication is only prescribed if enrolled in the protocol. Actual product packaging may appear differently than shown.

Why Rapamycin?

Preserve Functional Ability

Proven to extend the lifespan of every organism tested so far

Manageable & Preventable

Shown to improve healthspan and quality of life in aging adults

Safe & Consistent

Ongoing monitoring with our expert medical staff, all included

Featured in:

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BBC Science Focus


How does the process work?

Once approved, you will receive an automated message in your AgelessRx portal with the link to schedule your blood draw and a copy of your requisition form.

Your blood work is required to determine your continued eligibility. It should be completed as soon as possible. Once received, our experts will review your results and notify you of your approval status.

If you are approved, our team will generate a prescription for you with our partnering, US-based pharmacy. You will also receive updates and tracking information for your first shipment and all subsequent shipments through your AgelessRx portal.

From there, you will continue to provide blood work, fill out questionnaires, and meet as needed with our AgelessRx physician to track any benefits/side effects and determine that you remain eligible.

Who is eligible?

You must be at least 40 years of age, clinically stable, and in relatively good health (all of which will be assessed during your initial and ongoing visits) to take Rapamycin. You must also be able to give informed consent of your willingness to take off-label Rapamycin and to undergo routine blood work, as well as technologically capable to join virtual meetings and fill out online forms. There are no limitations on sex or ethnicity, and no maximum age limit.

How often do I take Rapamycin?

If, after doctor review and screening, you are approved for Rapamycin, you will only take one dose of Rapamycin each week. You may take more than one pill as part of your titration plan, but the frequency will not change.

What dose will I receive?

Generic Sirolimus is taken on a titrated plan to move from 2mg to 6mg per week over three months, ultimately ending at 6-8mg (at the discretion of the prescriber). You can only receive medication following a medical review and initial screening.

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Important safety information and common side effects

The information outlined on this page is exclusive to AgelessRx. Not all who request Rapamycin will be eligible.

By completing a free visit, you have the opportunity to consult with an AgelessRx prescriber about your health, medical history, and lifestyle. Your prescriber will use this information to evaluate your overall health and, if appropriate, prescribe medication in tandem with monitoring.

If approved, you will receive a doctor-guided monthly titration plan to gradually introduce Rapamycin to your body, so you can enjoy minimal side effects and maximal benefits. Your titration plan is determined based on your unique medical history; it may differ from standard titration plan, listed above. Always follow the instructions of your provider when titrating with Rapamycin. Your titration will be clearly listed on your Rx bottle as a reminder.

You are required to complete baseline blood work before your prescriber considers whether Rapamycin is right for you. Patients who do not complete their baseline blood work will not be considered for a Rapamycin prescription. You must also complete ongoing blood work, report any benefits or side effects, and fill out periodic questionnaires to determine your continued eligibility. Failure to comply with blood work or other reporting requirements may result in your prescription being suspended or canceled.

Most common Rapamycin side effects

Rapamycin is generally a well-tolerated medication and most often exhibits the following minor side effects:

  • Mouth ulcers (stomatitis)
  • Nausea
  • Diarrhea

Most side effects are mild and go away on their own within a week or two. If you notice a persistent infection, such as a mouth ulcer that won’t go away as quickly as normal, please consult your healthcare provider.

Please review the Mayo Clinic’s full list of possible side effects before getting started with a free visit.

Other important safety information

As a substrate for p-glycoprotein and cytochrome P-450 3A4, Rapamycin may have certain interactions with other drugs or supplements that act on these proteins. These include cyclosporine, rifampin, ketoconazole, cidofovir, ritonavir, mifepristone, posaconazole, fluconazole, and grapefruit juice.

Before taking Rapamycin, be sure to review the full list of potential drug interactions and talk to your healthcare provider about any medications you are currently taking.

Do not take Rapamycin if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. Do not take Rapamycin if you are scheduled to undergo major surgery, chemotherapy or immunosuppressant therapy for a transplant within the next 6 months; have a chronic infection (such as HIV/AIDS, Lyme disease, etc.), have any primary or secondary immune dysfunction or deficiency, and/or any allergy to Rapamycin or any of its ingredients.

While rare, it is possible that some who take Rapamycin may potentially become more susceptible to skin and/or lung infections. However, this is still being investigated and is not a proven risk associated with Rapamycin when taken at the frequency and doses prescribed at AgelessRx. If, at any time, you feel you are developing a troubling skin or lung infection, seek care at a local urgent care center, contact your PCP, or use an acute-care telemedicine service as soon as possible. Be sure to report the details to our medical team when you are able.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Please be advised that failure to participate in the initial or ongoing reporting requirements (including labs and questionnaires) will result in immediate termination of your eligibility to participate in this protocol and/or suspension of treatment.