What is Microdosing GLP-1?
GLP-1 medications may activate key biological pathways that support longevity¹ ². Taking smaller (micro) doses may also lower the risk of side effects⁴, creating a harmony with your body’s natural processes that may help you live healthier, longer.**
Get startedMICRODOSING GLP-1 BENEFITS
Do More, Age Less
- May modulate inflammatory pathways¹
- May reduce risk of cognitive decline²
- May support cardiovascular health³
- May improve mitochondrial function and oxidative stress²
- Low doses may reduce side effects⁴
*See studies cited below.
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- Low-dose Oral Semaglutide Drops
- Taken 3x weekly under the tongue, no needles necessary
- On-demand provider support and doctor-guided titration schedule
- Shipped free from a US-licensed pharmacy
CODE MICRO99: $99 for first month & FREE medical evaluation ($129/month after)
Microdosing GLP-1 is not available in AL, AR, MS, and VA.
You will be automatically billed & sent refills based on your plan
You can pause or cancel at any time before your next shipment
The FDA has not approved or reviewed the Microdosing Semaglutide dosing protocol or Oral Semaglutide Drops for safety, efficacy, quality, or for any use, including the AgelessRx compounded product.
*Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. See below for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.
**AgelessRx’s compounded Oral Semaglutide Drops have not been reviewed or approved by the FDA or analyzed by any available scientific study. However, our medical experts expect that Microdosing GLP-1 Oral Semaglutide Drops may sustain many of the same benefits that low doses of Semaglutide-based injection medications have shown individually in the studies cited above.
¹J Clin Tran Endo, 2024. This review study analyzes human GLP-1 trials, including protocols via injection that may be considered low dose or microdosing.
²Aging and Disease, 2022. This review study analyzes human and animal trials of various GLP-1 medications for their role in addressing the hallmarks of aging, such as mitochondrial function and oxidative stress, including low-dose protocols via injection for Parkinson’s patients on exenatide.
³NEJM, 2016. The SUSTAIN 6 clinical trial, sponsored by Novo Nordisk, explores cardiovascular outcomes for patients taking Semaglutide injections at doses as low as 0.5mg.
⁴JAMA Network, 2022. A human trial analyzing patients on Semaglutide injections that shows patients who stopped at lower doses of GLP-1 medications experienced less side effects.
FAQs
How do you microdose with GLP-1?
Microdosing Semaglutide is a low-dose prescription of Oral Semaglutide Drops, which is taken by dropping the medication under your tongue.
To take Oral Semaglutide drops, carefully draw up your prescribed dose by inserting the oral syringe (that comes with your prescription) into the solution bottle; then squeeze the contents under your tongue.
Hold the medication under your tongue for as long as possible, or at least 90 seconds. Do this three times each week, unless you’re prescribed otherwise.
Microdosing Semaglutide uses the smallest measurements on your oral syringe. Measuring the correct dose is easy, but so is overmeasuring. Pay extra attention to the measurements on your oral syringe to ensure that you’re receiving the most accurate dose.
Can I transition to a regular dose if needed?
The max dose for Microdosing Semaglutide is 0.4ml every three days. If you’re looking for a higher dose, explore weight loss solutions that may be a better fit for your health goals.
See all FAQsImportant safety information and common side effects
Microdosing Semaglutide should be used with a reduced-calorie meal plan and increased physical activity.
Oral Semaglutide Drops contain Semaglutide and should not be used with other GLP-1 receptor agonist medications, or any other products containing Semaglutide.
Side effects
Microdosing Semaglutide is a low-dose Oral Semaglutide Drops prescription.
Oral Semaglutide Drops has not been evaluated by the FDA, but side effects are expected to be similar to other GLP-1 medications reviewed by the FDA, which have the following side effects: nausea, diarrhea, vomiting, constipation, abdominal (stomach) pain, headache, fatigue, dyspepsia (indigestion), dizziness, abdominal distension, eructation (belching), hypoglycemia (low blood sugar) in patients with type 2 diabetes, flatulence (gas buildup), gastroenteritis (an intestinal infection), and gastroesophageal reflux disease (a type of digestive disorder).
Common side effects normally go away on their own within a few days or up to 2-3 weeks. Read our blog for more tips on how to manage Semaglutide side effects. If you find that any side effects persist for longer than this or get worse over time, stop taking your medication and contact your prescriber as soon as possible. For a full list of side effects, please review the Mayo Clinic’s GLP-1 resources.
Other important safety information
Do not use Semaglutide if you have a personal or family history of medullary thyroid carcinoma (MTC), multiple endocrine neoplasia syndrome 2 (MEN2), or pancreatitis.
The FDA is currently evaluating whether GLP-1 medications may increase the risk of suicidal thoughts or actions. Though the FDA has found no evidence supporting this risk, patients with a history of suicidal thoughts should not take Semaglutide.
Do not use Semaglutide if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed.
Though rare, allergic reactions to Semaglutide are possible. If you notice any shortness of breath or swelling around your face, tongue, or throat after using Semaglutide, stop using the medication immediately and contact emergency services right away.
As with any prescription medicine, the dose prescribed is for you and you alone. Do not, under any circumstances, allow anyone else to use your Oral Semaglutide Drops.
Tell your healthcare provider about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Tell your healthcare provider if you are taking any medications to treat diabetes, including sylfonylureas or insulin.
Note: This product alone is not intended to diagnose, treat, cure, or prevent any disease. Please consult a medical professional to determine whether or not Semaglutide is appropriate for you.