Glutathione is the body’s master antioxidant, naturally produced by the liver and nervous system, that helps protect cells from damage and support overall health. But as we age, our natural Glutathione levels slowly decline, which can lead to oxidative stress, inflammation, and cellular damage. Glutathione Injections help replenish our Glutathione levels, potentially preventing conditions that can lead to age-related disease.

Before you get started, read more about important usage information for Glutathione Injections.

Quick tips

Here are some simple steps to help you get the most from each dose:

• Refrigerate your vials upon arrival
• Take Glutathione around the same time with each dose
• Can be taken with or without food
• Rotate injection sites with each dose
• Be sure to properly discard vials and syringes

Follow these tips to give yourself the best chance to experience the best possible benefits while minimizing side effects.

Getting started

When you first receive your prescription, ensure proper storage guidelines to maintain the quality of the solution.

Follow the instructions for drawing and administering your medication.

Always dose according to your doctor-guided titration schedule. 

Learn the best strategies for reducing potential side effects.

Storage

To maintain the utmost quality, it is best to refrigerate your vials between 36°F and 46°F. If your vial has been stored below 36°F or above 46°F for an extended time, the solution may become ineffective.

All vials indicate the date by which the medication should be used. This is at least 180 days after the medication was compounded, the date of which will clearly listed on the medical label. Please use the medication before the beyond-used date (BUD). 

Once you pierce the vial, the solution will last for 28 days. You must discard pierced vials after 28 days, even if there is still some solution remaining—this applies to all multi-dose vials (MDVs). 

Upon receiving your medication, check the temperature of the vials with the back of your hand. If it feels hot to the touch, please contact us immediately. 

You may safely travel with your vials so long as the above conditions are met while traveling. Be sure to travel with a refrigerated case if necessary, and to bring your own sharps disposal container if you will not have access to one.

Drawing and administering

How to draw your solution

Before your first use, take the time to review how to properly draw your solution. 

Next, ensure that you are drawing the correct amount of solution according to your titration schedule. Your current dose will always be displayed on your vial—use this as a reminder before you begin.

It is important to sterilize the top of the vial with an alcohol wipe each time before drawing up the solution.

How to measure units on your syringe

If you’re new to subcutaneous injections, follow this quick guide to understand the measurements on your syringe.

Your weekly doses are measured in milliliters (ml) to units. Before getting started, check to see how many units are in your weekly dose.

The label on your subcutaneous syringe shows units. Each unit represents 0.01ml, so every 10 units represents 0.1ml.

Each small line on the syringe represents 1 unit, and each large line represents 10 units. So, if your dose calls for 20 units, simply draw your solution up to the line that reads “20.”

If your weekly dose calls for a measurement not clearly labeled on the syringe (like 25 units), pay close attention to the markers between the large lines when drawing up your dose. There may be even smaller measurement lines on the syringe that are more difficult to see. Count these carefully as you draw up your dose to ensure the most accurate measurement.

How to administer your solution

Glutathione Injections are delivered via subcutaneous injection, which means that you will inject the solution into a fatty layer of tissue, such as your abdomen or your thigh. If you’re new to self-administered injections, take the time to review how to properly administer your injection before proceeding.

As a general rule, you should grip the syringe with your dominant hand, and grasp the injection site with the other hand. 

If you can grasp at least 2 inches of skin, then deliver the injection at a 90° angle (or, straight in). If you cannot grasp at least 2 inches of skin, deliver the injection at a 45° angle.

To avoid irritation, try switching injection sites with each dose. You can take Glutathione with or without food, and at any time of day, but try to be as consistent as possible to ensure the best outcomes.

After you have administered your injection, discard the needle and syringe in an FDA-approved sharps container. Never reuse the needle or the syringe once it has been used.

Glutathione Injections titration schedule

Glutathione Injections can be taken up to 5 times per week, at a dose between 0.1ml (10 units) and 0.5ml (50 units). 

This flexible dosing schedule allows you to gradually introduce the medication to your body at a pace that works best for you. This way, you have the best opportunity to experience the greatest benefits possible while reducing side effects. Here how to get started:

• In your first weeks:
  Start by taking 0.1ml (10 units), 2-3x per week.
  
• If you don’t have side effects:
  Increase your dose by 0.1ml (10 units) every 1-2 weeks, as tolerated. You can also increase how often you take Glutathione Injections by 1 day per week, every 1-2 weeks, as tolerated.
  
• If you do experience side effects:
  Stay at your current dose, or reduce how often you take it. When you’re ready, or when your side effects subside, increase your dose by 0.1ml (10 units) per week as tolerated.

Here is a general guide to how your titration might progress; use these as monthly targets as you continue your Glutathione journey:

Week	Dose	Frequency
Weeks 1-2	0.1ml	2-3x per week
Weeks 3-4	0.2ml	3-4x per week
Weeks 5-6	0.3ml	3-5x per week
Weeks 7-8	0.4ml	3-5x per week
Weeks 9+	0.5ml	3-5x per week

Each shipment will always include enough medication to accommodate the maximum prescribed dose at the maximum recommended weekly frequency (0.5ml for 5 days per week). 

If you miss a dose, you can skip the dose you missed and take it the next day. Never take more than your prescribed dose. If more than 2 weeks have passed since your last dose, please contact your prescriber for further guidance: you may be asked to restart your titration.

If you feel you’re not meeting your health goals at the maximum dose and frequency, please contact your prescriber.

Side effects

Glutathione Injections have not been evaluated by the FDA, but our patients report* the following side effects:

• Diarrhea (35.8%)
• Upset stomach (29.2%)
• Fatigue (19.2%)
• Nausea (19.1%)
• Stomach cramping (13.3%)

Most side effects go away on their own within a few days or weeks. If you find that any side effects persist longer or get worse over time, stop taking your medication and contact your prescriber as soon as possible.

*Actual results may vary. Data was self-reported by 17,084 surveyed customers who checked in with their provider between 4/7/2022 and 8/18/2025. All respondents are AgelessRx customers who were approved for a prescription after completing an assessment with a medical provider.

Important safety information

Do not use Glutathione if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed.

Taking Glutathione long term may lead to lower zinc levels. Symptoms of low zinc levels include getting sick often, loss of appetite, hair loss, and brittle or discolored nails.

Though rare, allergic reactions to Glutathione are still possible. If you notice any shortness of breath or swelling around your face, tongue, or throat after using your treatment, stop use immediately and contact emergency services right away.

As with any prescription medicine, the dose prescribed is for you and you alone. Do not, under any circumstances, allow anyone else to use your treatment.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.