B12 INJECTION BENEFITS
Take control of your health
- May fight fatigue and boost natural energy levels¹
- May encourage higher quality sleep for better rest²
- May improve mental sharpness³ and mood stability⁴
- May promote healthier skin⁵, nails⁵, and metabolic function⁶
- Shown to support cardiovascular health⁷ and bone density⁸
- Tested for purity by US-licensed pharmacies
B12 INJECTION
The science of B12
- B12 is vital for the body’s needs, but can’t be self-produced⁹
- Up to 15% of Americans lack sufficient B12 levels¹⁰
- Nutrition gaps, gut health issues, and menopause or andropause may increase risk of B12 deficiency¹¹
- Subcutaneous injection delivers B12 directly into the bloodstream for quick, efficient absorption
Science-backed treatment, real results
92% of patients saw improvements by their second check-in
88% felt more energized
85% felt reduced fatigue
76% observed improved mental clarity
*Actual results may vary. Data was self-reported by 1,412 surveyed customers who checked in with their provider on their second check-in between 4/1/23 and 4/1/24. All respondents are AgelessRx B12 Injection customers who were approved for a prescription after completing an assessment with a medical provider.
How it works
Simple consultation
Connect with our US-licensed medical prescribers online to see if B12 is right for you, no office visit required.
Free shipping
If approved, your prescription will be fulfilled by one of our US-licensed, 503A certified pharmacy partners and rigorously inspected for quality before arriving at your doorstep in 5 days or less.*
Continuous support
Enjoy ongoing access to providers, easy refills, and direct updates from your prescriber, ensuring support throughout your journey.
*Shipping times do not include pharmacy processing or doctor approval; your AgelessRx provider will take 1-2 days to review your request and send to our partner pharmacy, who will take an additional 2-3 days to process. Shipping times may be affected by regional variability. Temperature-sensitive medications are subject to state and federal requirements and may take longer to ship.
Ready to get started?
Start your free online visit now.
You will be automatically billed & sent refills based on your plan
You can pause or cancel at any time before your next shipment
* Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. See below for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown. Please allow 3-5 days for processing & shipping following medical approval.
FAQs
Why should I choose an injection over an OTC supplement?
Injections have better bioavailability than oral supplements as they bypass the digestive system completely, providing a direct supply of B12 into the bloodstream to fuel your body. Oral supplements might work for some, however, as we age, our ability to break down oral supplements often decreases.
How much B12 is administered per injection?
The solution contains 1000mcg of B12 per mL/cc.
How often do I administer the injections?
Start by injecting 1ml/cc per injection once per week. If you feel you’re not getting your expected results, please contact your prescriber.
How can B12 shots help with longevity?
B12 shots aren’t just a great way to enjoy more energy throughout the day. In fact, B12 shots can also improve our cognitive function, maintain our vision, and lower our risk for age-related conditions like osteoporosis, macular degeneration, and cardiovascular disease. B12 shots also help us to look as good as we feel by promoting better sleep and healthier skin and nails.
What type of B12 does AgelessRx offer?
We offer Methylcobalamin B12 injections for all states except California and New York. Due to state regulations, patients located in California and New York will receive Cyanocobalamin B12 injections.
See all FAQsImportant safety information and common side effects
The most common side effect of B12 injections is irritation at the injection site. If this occurs, consider changing placement on the body or use injections less often.
For a complete list of possible side effects, click here.
Do not use B12 injections if you are currently pregnant, breastfeeding or plan to become pregnant or breastfeed.
Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Show me the science
All our claims are backed by science, and we’ve got the receipts. Because when it comes to your health, you shouldn’t have to guess.
| 1. This observational study examined 38 patients with chronic fatigue syndrome who were supplementing with B12 and folic acid, showing improvements to chronic fatigue symptoms. | PLoS One, 2015 |
| 2. A cross-sectional study of 512 participants with sleep issues who self-reported better sleep quality after supplementing with B12. | Healthcare (Basel), 2023 |
| 3. This open-label study collected B12 data from dementia patients treated at Fukui or Nakamura Hospital between 2008 and 2021, showing B12 supplementation improves cognitive function for those with B12 deficiency. | Nutrients, 2022 |
| 4. A review of 40 published studies on B12, which concludes that B12 deficiency is associated with a higher risk of depression symptoms. | Cureus, 2020 |
| 5. This review analyzes the history of B12 use to address skin and nail health in those with B12 deficiencies. | AJCD, 2015 |
| 6. A randomized clinical trial of 80 participants with type 2 diabetes showing that B12, alone and with folic acid, improves HbA1C and insulin resistance | Comp Ther Med, 2020 |
| 7. This review study analyzes studies using vitamin B supplementation to reduce CVD symptoms, concluding that B12 supplementation is associated with a lower risk of CVD in healthy patients. | Nutrition Reviews, 2023 |
| 8. A case study following a patient with severe osteoporosis and pernicious anemia where symptoms were improved with B12 replacement therapy. | Metabolism, 1994 |
| 9. Harvard Health general information page on B12 deficiency. | Harvard Health, 2022 |
| 10. Cleveland Clinic information page that confirms the general rate of B12 deficiency. | Cleveland Clinic |
| 11. This review study provides a comprehensive overview of the various health conditions associated with B12 deficiency. | Nutrients, 2010 |
| 12. A review of vitamin B12 in health and aging and how homocysteine levels and B12 levels are related to the development of age-related diseases. | Int J Lab Med, 2013 |
| 13. A longitudinal study presenting evidence for the role of B12 in cognitive function. | Brain Disorders, 2025 |