Longevity Science 101

What is aging?

Aging is marked by a progressive loss of physical integrity, with lessened functionality and increased vulnerability to death. It occurs due to a series of processes such as accumulation of cellular waste, errors, and imperfect repairs, as well as direct damage to the cells. These processes result in the familiar signs of aging and ultimately lead to the development of age-related diseases that eventually kill us.

Aging is a predominant risk factor for most common chronic diseases that limit health span.

Aging is not inevitable

A common misconception is that aging is inevitable. However, in the last 10 years our understanding of aging and the processes that drive it has improved materially. Scientist have shown that aging is not inevitable, and is actually a malleable thing, which can be slowed down and even reversed if we adjust the proper “levers.”

Rogina Blanka was able to extend a fly’s lifespan 2-fold by creating a mutation in the indy gene.

Andrzej Bartke was able to extend a mouse’s lifespan 2-fold by mutating the growth hormone receptor gene and by restricting calorie intake.

Source: Kurzggesagt & Lifespan.io

Science reveals slowing the aging process is a realistic goal

No longer is aging being treated as a dreadful inevitability but instead as a puzzle that can be solved—as a disease with a cure.

Time Special Edition, April 2019

Example: senescent cells research

Senescent cells have been shown to contribute to age-related disease (arthritis, cataracts, etc.) in mice. Elimination of these senescent cells has had a significant impact on aging and improved healthspan in multiple animal studies across independent labs. One study even found that clearance of senescent cells led to a significant increase (~35%) in median lifespan (Baker, D. J. Nature 2016).

The 9 hallmarks of aging: a framework for research

In 2013 a team of researchers attempted to identify and categorize the cellular and molecular hallmarks of aging.

They broke down the causes of aging into 9 distinct scientific “hallmarks” and explained how these interact with each other to drive the onset of age-related diseases.

Today there are multiple available therapies, with many more being researched, that use this framework to directly intervene against the aging process.

Metformin

Metformin – a simple, once-daily medication used to treat diabetes – may also help support glucose control, encourage weight loss, and reduce the risk of certain age-related diseases.

Starting at $25

NAD+ Patches

A pain-free alternative to NAD injections, using once-weekly iontophoresis patches to deliver NAD+ into the bloodstream. Compounded and made-to-order by a certified pharmacy.

Starting at $160

Low Dose Naltrexone

Unlike other treatments, Low Dose Naltrexone (LDN) has been shown to work with your immune system to potentially reduce pain, restore energy, and improve quality of life.

Starting at $35

NAD+ Nasal Spray

A convenient way to boost brain NAD+ levels without the injection, formulated to help improve energy, mental clarity, and mood as needed while on the go.

Starting at $125

Rapamycin

Explore the most promising longevity therapy today, with ongoing monitoring and blood work included with your prescription.

Starting at $65

Prescription products require an online consultation with a physician who will determine if a prescription is appropriate. See product page for important safety information. Benefits outlined on agelessrx.com are based on 3rd party studies.