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Methylene Blue

  • Pill

A science-backed antioxidant with diverse longevity potential, Methylene Blue may boost focus, brain health, and cellular energy, unlocking peak cognitive performance without the mess of drops.

Starting at $43

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Methylene Blue benefits

May improve memory, focus, mental clarity, and overall cognitive function

May enhance mitochondrial energy

May stifle inflammation in the brain that contributes to brain fog

May protect against oxidative stress & free radical damage

May slow age-related cognitive decline and neurodegenerative diseases like Alzheimer’s

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The science behind Methylene Blue

Methylene Blue is a metabolic enhancer with antioxidant, antimicrobial, and neuroprotective properties shown to support cognitive function, immune function, long-term cellular health, and overall healthspan.

  • Methylene Blue works by entering damaged mitochondria—the energy engines of your cells—to help restore ATP production.
  • As we age, damaged mitochondria accumulate and reduce cellular efficiency, contributing to gradual cognitive decline.
  • ATP is the fuel our cells need to repair, grow, and function at their best.
  • By boosting ATP production, Methylene Blue helps cells work more efficiently—giving neurons the energy they need to keep the brain healthy.

What to expect

blue-pills

1 Day

Methylene Blue begins restoring mitochondrial function right away, potentially stimulating blood flow and adaptive changes in the brain after the first dose.

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1 Week

Users may experience better mental clarity and learning ability as Methylene Blue starts enhancing functional connectivity in the brain.

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1 Month

By the end of the month, Methylene Blue may boost immune function and oxygen delivery, enhancing overall health and recovery.

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3 Months

By now, Methylene Blue may be protecting your brain from oxidative stress, neuroinflammation, and mitochondrial damage to combat the drivers of brain aging.

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6 Months

Enhanced memory, focus, and mental clarity transform into lasting cellular changes that may resist age-related decline.

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1 Year+

With continued use, Methylene Blue may protect against brain degeneration while enhancing overall brain metabolism.

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Quarterly
$43 / month billed $129 quarterly | free shipping
  • Oral Methylene Blue capsules
  • Taken 3x weekly
  • Ongoing medical support
  • Doctor-guided titration schedule
  • Tested for purity by a certified US-licensed pharmacy

CODE METHYLENEBLUE99$30 off first shipment & FREE medical evaluation

You can pause or cancel at any time before your next shipment

* Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. See below for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.

The FDA has only approved Methylene Blue for treatment of acquired methemoglobinemia, and has not approved or reviewed Methylene Blue for safety, efficacy, or quality related to any other uses, including longevity.

FAQs


How do you take Methylene Blue?

Methylene Blue capsules are taken by mouth with a full glass of water. For the best results, take Methylene Blue in the morning at around the same time. You can take Methylene Blue with or without food, but taking your dose after breakfast may help minimize the risk of gastrointestinal side effects.


Will Methylene Blue capsules stain my teeth?

Nope! Unlike Methylene Blue drops, capsules protect your teeth from discoloration. However, you should still expect the medication to turn your urine blue, which is a known and harmless side effect. 

When encapsulated, the Methylene Blue solution doesn’t come into direct contact with your teeth, tongue, cheeks, or any part of your mouth—it’s swallowed whole so it can be more easily absorbed. 

But capsules only protect from discoloration if they remain intact. If you break the capsule, the medication will likely stain anything it comes into contact with. Avoid chewing or separating your Methylene Blue capsules.


I broke my Methylene Blue capsules, how do I remove the stain?

If you chewed your capsule and it stained your mouth, tongue, or teeth, try swishing your mouth with lemon juice or vinegar water for 30 seconds, then rinsing. Repeat this step several times if necessary. You should also stay hydrated and drink as much water as possible.

If Methylene Blue stains your skin or clothes, try scrubbing with the same lemon juice or vinegar water solution, or using a full-strength, skin-safe detergent. You can remove Methylene Blue from objects or surfaces with most commercial stain removers. Please note that there is no reliable method to reduce the appearance of blue urine after taking Methylene Blue. In most cases, urine will not clear until 2-6 hours after your last dose, or up to 24 hours.

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Important safety information and common side effects


Most common side effects

One of the most common side effects of Methylene blue is blue urine, which is a normal reaction and not cause for alarm. Feces, saliva, and sweat may also be temporarily discolored with a blue tint. Most patients clear the medication from their system within 4-6 hours, or up to 24 hours.

Some patients may also experience sun or UV sensitivity while taking Methylene Blue. Be cautious when spending time in the sun, even artificial sunlight, and go inside if necessary.

Other common side effects include nausea, vomiting, stomach pain, diarrhea, loss of appetite, anxiety, and urinary irritation.

Most side effects are mild and go away on their own within a week or two. Taking Methylene Blue with a full glass of water and a meal may help minimize the chances of side effects.

Other important safety information

Methylene Blue should not be used by anyone with a history of G6PD deficiency, or anyone who has or has had renal dysfunction. 

Do not use Methylene Blue if you are currently taking a medication that affects serotonin, such as antidepressants like SSRIs and MAOIs, or SARIs like Trazodone

Do not use methylene Blue if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed while taking Methylene Blue.

Though rare, allergic reactions to methylene Blue are still possible. If you notice any shortness of breath or swelling around your face, tongue, or throat after using methylene Blue, stop use and contact emergency services right away.

As with any prescription medication, the dose prescribed is for you and you alone. Do not, under any circumstances, share or allow anyone else to use your Methylene Blue prescription.

Note: This product alone is not intended to diagnose, treat, cure, or prevent any disease. Please consult a medical professional to determine whether or not Methylene Blue is right for you.