Here’s what we’ll cover in this blog post:
- Can Metformin help you live longer?
- Results from the latest Metformin science
- What the study says
- What this means for you
Can Metformin help you live longer?
That’s the question on every longevity enthusiast’s mind, and the question that has been driving Metformin research for decades. But has anybody provided a definitive answer?
Initial studies and anecdotal evidence suggest that Metformin can increase the number of healthy years we enjoy. However, a recent study may finally give a clear response, providing some of the most compelling real-world evidence associating Metformin with exceptional longevity.
So, how does this study finally answer the question—can Metformin help you live longer? Let’s take a closer look at the findings and what it means for the future of Metformin.
Can Metformin Help You Live Longer?
According to this 2025 study, Metformin may reduce the risk of death before age 90 by up to 30%.
Using data from the Women’s Health Initiative, a long-term US study tracking over 161,000 postmenopausal women since the 1990s, researchers focused on a subgroup of 438 women. This group were all at least 60 years old and all had type 2 diabetes. The participants took either Metformin or sulfonylurea, another popular diabetes mediation.
The researchers found that those taking Metformin had a 30% lower risk of dying before age 90 when compared with the sulfonylurea group. In other words, Metformin improved the chances of living to 90 by 30%.
What Do the Results Mean?
This is the first study designed to determine whether Metformin is associated with exceptional longevity, which is typically defined as living to 90-100 years or more.
But there were some caveats to the study: only women were participants, all had type 2 diabetes, and there was no placebo group. Overall, this was an observational study, rather than a full-blown clinical trial. For these reasons, researchers can’t conclude confidently that Metformin causes exceptional longevity.
But causality was beyond the scope of the study, and the results still mark an incredible milestone for Metformin and longevity science. This study focuses uniquely on whether Metformin use can help users live past 90, an objective marker of longevity, and the results seem to answer a resounding “yes.”
Now, there’s little doubt in the scientific community that Metformin is a potential candidate as a longevity medication. Earlier studies show that Metformin may lower cancer and heart disease risk, while other studies suggest that metformin can improve cognitive function.
Meanwhile, the long-term TAME trial means to show once and for all that prescribers may be able to repurpose Metformin as a gerotherapeutic medication. This could pave for Metformin to become the first FDA-approved longevity medication.
What Does This Mean for Me?
Though this study was only for women with type 2 diabetes, there’s a wealth of science supporting Metformin for its potential longevity benefits for healthy individuals.
This new study offers compelling, real-world support for Metformin as a gerotherapeutic, or a longevity medication. Though scientists need more studies, a 30% lower risk of dying before age 90 is a powerful statistic.
Even if you don’t have diabetes, Metformin can help optimize your health for years to come —and you can get Metformin fast, easy, and 100% online with AgelessRx.
We believe in empowering people to take control of their health, giving you access to the tools you need to improve not just how long you live, but how healthy you live. That means making it easy to request Metformin and manage your prescription, with licensed providers and personalized medical support at your fingertips.
If you’re curious about what Metformin can do for your long-term health, why wait? Just because aging is inevitable, doesn’t mean we can’t control how we age. Get started with a free medical intake today to see if Metformin is right for you.
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Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.