FDA approved for weight management, Wegovy® contains the active ingredient Semaglutide, a GLP-1 receptor agonist that helps manage blood sugar and appetite, keeping you fuller for longer.

If you’ve received this guide, your AgelessRx provider has approved your request for a Wegovy® prescription and sent your prescription to NovoCare. The next step is to respond to the text messages you will receive from NovoCare to confirm your personal details and provide payment for your treatment.

Read below for tips on how to draw and administer your injection, and what to expect while using Wegovy®.

Next Steps for NovoCare

Quick tips

Here are some simple steps to help you get the most from each dose:

• Refrigerate your injection pens upon arrival
• Keep your pens in the original container
• Use with a reduced-calorie meal plan and exercise
• Take Wegovy® on the same day each week
• Can be taken with or without food
• Rotate injection sites every week

Follow these tips to ensure that you experience the best possible benefits while minimizing side effects.

Getting started

When you first receive Wegovy®, ensure proper storage guidelines to maintain the quality of the solution.

Follow the instructions for how to use Wegovy®.

Always dose according to your doctor-guided titration schedule.

Learn the best strategy for reducing side effects in your first weeks.

Storage

To maintain the utmost quality, keep your injection pens in the original container and refrigerate them between 36°F and 46°F. If necessary, you can store an unopened Wegovy® pen at room temperature (46°-86°F). If the medication has been stored below 46°F or above 86°F for an extended time, the solution may become ineffective.

Before using the injection pens, check that the solution is clear and colorless. If it appears cloudy or discolored, call NovoCare Customer Support at +1 (888) 809-3942.

You may safely travel with Wegovy® so long as the above conditions are met while traveling. Be sure to keep your medication in its original container, or keep your pens in a refrigerated travel case for the duration of your trip. Bring your own sharps disposal container if you will not have access to one.

How to use Wegovy®

Wegovy® is taken as a subcutaneous injection, which means you’ll self-inject the medication into a layer of fatty tissue such as your abdomen or thigh. If this is your first time using Wegovy®, please review the Novo Nordisk Wegovy tutorial video before getting started.

Start by selecting where you’ll administer the injection and clean the area.

Next, remove the needle cap from the pen and hold the pen firmly against your skin at a 90° angle (or straight in), then use your thumb to press and hold down the button at the end of the pen.

Hold the button for at least 10 seconds. In this time, you’ll hear 2 clicks. The first lets you know that the injection has started. The second lets you know the injection is ongoing and nearly complete. The yellow bar in the dose window should also start moving. If you don’t hear the first click or see the yellow bar start moving, restart the steps and try to hold the pen more firmly against your skin. 

Once you’ve heard both clicks and the yellow bar has stopped moving, slowly remove the pen from your skin. Each Wegovy® pen is single-use, so discard the pen in an FDA-approved sharps disposal container as soon as you’re finished. Never save or reuse your Wegovy® pens.

Titration instructions

Wegovy® is available in 5 different doses: 0.25mg, 0.5mg, 1mg, 1.7mg, and 2.4mg.

Each month’s order contains 4 injection pens that are prefilled with your prescribed dose. At the end of each month, you will titrate up to the next highest dose until you reach the maximum dose of 2.4mg per week.

Which dose you are prescribed will vary depending on your health goals, medical history, and whether you were recently taking another GLP-1 medication.

Month 1	0.25mg	Once weekly
Month 2	0.50mg	Once weekly
Month 3	1mg	Once weekly
Month 4	1.7mg	Once weekly
Month 5+	2.4mg	Once weekly

If you forget your titration schedule, you can always check your AgelessRx portal.

If you missed a dose of Wegovy® and your next scheduled dose is more than 2 days away, take your dose as soon as possible. If your next scheduled dose is less than 2 days away, skip the dose you missed and take the next dose when you normally would. If you miss a dose for more than 14 days, your AgelessRx prescriber may recommend that you restart your titration schedule.

Common side effects

Wegovy® has the following side effects: nausea, diarrhea, vomiting, constipation, abdominal (stomach) pain, headache, fatigue, dyspepsia (indigestion), dizziness, abdominal distension, eructation (belching), hypoglycemia (low blood sugar) in patients with type 2 diabetes, flatulence (gas buildup), gastroenteritis (an intestinal infection) and gastroesophageal reflux disease (a type of digestive disorder).

Common side effects normally go away on their own within a few days or up to 2-3 weeks. If you find that any side effects persist for longer than this or get worse over time, stop taking Wegovy® and contact your prescriber as soon as possible

To help prevent side effects from occurring or persisting, try the following:

• Eat slower and at more regular intervals throughout the day
• Try to take Wegovy® at about the same time of day each week
• Drink only water or clear, unsweetened beverages
• Avoid fried, greasy foods in favor of healthier, low-fat options

This is only a summary of potential side effects and how to address them. For more information, please reference the Mayo Clinic’s Semaglutide resources, or ask your prescriber. 

Serious side effects

Semaglutide has been associated with the following rare but serious side effects:

• Thyroid C-cell tumors
• Diabetic retinopathy
• Hypoglycemia
• Kidney problems
• Gallbladder problems
• Pancreatitis
• Worsening of mood

Your AgelessRx prescriber will weigh these potential risks against your unique medical history when considering a prescription.

For a full list of potential warning signs for these conditions, please see the Mayo Clinic’s Semaglutide resources.

Important safety information

Wegovy® should not be used by anyone who has a personal or family history of medullary thyroid carcinoma (MTC), multiple endocrine neoplasia syndrome 2 (MEN2), or pancreatitis. 

The FDA is currently evaluating whether GLP-1 medications like Wegovy® may increase the risk of suicidal thoughts or actions. Though the FDA has found no evidence supporting this risk, patients with a history of suicidal thoughts should not take Wegovy®.

Do not use Wegovy® if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed.

Semaglutide may make oral contraceptives less effective. If you’re taking an oral contraceptive, ask your prescriber about potential alternatives before starting Semaglutide, or switch to a non-oral contraceptive.

Though rare, allergic reactions to Wegovy® are still possible. If you notice any shortness of breath or swelling around your face, tongue, or throat after using Wegovy®, stop use immediately and contact emergency services right away. Mild allergic reactions around the injection site are normal and not cause for emergency.

As with any prescription medicine, the dose prescribed is for you and you alone. Do not, under any circumstances, allow anyone else to use your Wegovy®.