Wegovy® Pill Access & Monitoring Product Guide

FDA approved for weight management, Wegovy® Pill contains the active ingredient Semaglutide, a GLP-1 receptor agonist that helps manage blood sugar and appetite, keeping you fuller for longer.

If you’ve received this guide, your AgelessRx provider has approved your request for a Wegovy® Pill prescription and sent your prescription to Amazon Pharmacy. The next step is to create your Amazon Pharmacy account. You can create your account here on Amazon directly. Amazon Pharmacy will text or email you separately to verify your personal information and complete the remainder of your payment

Read below for tips on how to take your medication and what to expect while using Wegovy® Pill.

Quick tips

Here are some simple steps to help you get the most from each dose:

  • Keep your pills in their original bottle
  • Use with a reduced-calorie meal plan and exercise
  • Take Wegovy® Pill on an empty stomach in the morning
  • Must be taken with no more than 4 ounces (120 mL) of plain water
  • Do not split, crush, chew, or dissolve your tablets
  • After 30 minutes, you can eat, drink, or take other oral medicines

Follow these tips to ensure that you experience the best possible benefits while minimizing side effects.

Getting started

When you first receive Wegovy® Pill, ensure proper storage guidelines to maintain the quality of the pills.

Always dose according to your doctor-guided titration schedule.

Learn the best strategy for reducing side effects in your first weeks.

Storage

To maintain the utmost quality, keep your Wegovy® Pill in their original container. 

Store at room temperature (between 68°F and 77°F), and in a dry environment. Avoid storing your Wegovy® Pill in areas with excessive heat or humidity, like your bathroom, laundry room, or utility closet. Always keep your Wegovy® Pill where your children or pets can’t reach it. If the medication has been stored below 59°F or above 86°F for an extended time, the medication may become ineffective.

You may safely travel with Wegovy® Pill so long as the above conditions are met while traveling.

Titration instructions

The Wegovy® Pill is available in 4 different doses: 1.5mg, 4mg, 9mg, and 25mg. Each month’s order contains 30 pills of your prescribed dose. You are to take 1x Wegovy® Pill once daily, in the morning, on an empty stomach. Do not eat or drink for at least 30 minutes. After 30 minutes, you can eat, drink, or take other oral medications. At the end of each month, you will titrate up to the next highest dose until you reach the maximum dose of 25mg per day.

Which dose you are prescribed will vary depending on your health goals, medical history, and whether you were recently taking another GLP-1 medication.

Month 11.5mgOnce daily
Month 24mgOnce daily
Month 39mgOnce daily
Month 425mgOnce daily

If you forget your titration schedule, you can always check your AgelessRx portal.

If you missed a dose of Wegovy® Pill, skip the dose and go back to your regular schedule for the next dose. Do not take more than 1x Wegovy® Pill each day.

Common side effects

The Wegovy® Pill may have the following side effects: nausea, diarrhea, vomiting, constipation, abdominal (stomach) pain, headache, fatigue, dyspepsia (indigestion), dizziness, abdominal distension, eructation (belching), hypoglycemia (low blood sugar) in patients with type 2 diabetes, flatulence (gas buildup), gastroenteritis (an intestinal infection), gastroesophageal reflux disease (a type of digestive disorder), and runny nose or sore throat.

Common side effects normally go away on their own within a few days or up to 2-3 weeks. If you find that any side effects persist for longer than this or get worse over time, stop taking Wegovy® and contact your prescriber as soon as possible.

To help prevent side effects from occurring or persisting, try the following:

  • Eat slower and at more regular intervals throughout the day
  • Try to take your Wegovy® Pill at about the same time each day
  • Drink only water or clear, unsweetened beverages
  • Avoid fried, greasy foods in favor of healthier, low-fat options

This is only a summary of potential side effects and how to address them. For more information, please reference the Mayo Clinic’s Semaglutide resources, or ask your prescriber. 

Serious side effects

Semaglutide has been associated with the following rare but serious side effects:

  • Thyroid C-cell tumors
  • Diabetic retinopathy
  • Hypoglycemia
  • Kidney problems
  • Gallbladder problems
  • Pancreatitis
  • Worsening of mood

Your AgelessRx prescriber will weigh these potential risks against your unique medical history when considering a prescription. For a full list of potential warning signs for these conditions, please see the Cleveland Clinic’s Semaglutide resources.

Important safety information

The Wegovy® Pill should not be used by anyone who has a personal or family history of medullary thyroid carcinoma (MTC), multiple endocrine neoplasia syndrome 2 (MEN2), or pancreatitis. 

The FDA is currently evaluating whether GLP-1 medications like Wegovy® may increase the risk of suicidal thoughts or actions. Though the FDA has found no evidence supporting this risk, patients with a history of suicidal thoughts should not take Wegovy® Pill.

Do not use Wegovy® Pill if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed.

Semaglutide may make oral contraceptives less effective. If you’re taking an oral contraceptive, ask your prescriber about potential alternatives before starting Semaglutide, or switch to a non-oral contraceptive.

Though rare, allergic reactions to the Wegovy® Pill is still possible. If you feel faint or dizzy, experience very rapid heartbeat, or notice any shortness of breath or swelling around your face, tongue, or throat after using Wegovy® Pill, stop use immediately and contact emergency services right away. 

As with any prescription medicine, the dose prescribed is for you and you alone. Do not, under any circumstances, allow anyone else to use your Wegovy® Pill.

FAQs

How does the Wegovy® Pill work?

Wegovy® Pill works by imitating the natural GLP-1 hormone in the body that helps manage blood sugar and appetite. GLP-1 helps block glucagon, a hormone that increases blood sugar, stimulates insulin release from the pancreas after you eat, and signals with the gut and brain to reduce gut motility. This slows down digestion to help users feel fuller for longer.

How much weight can I lose?

Clinical trials have shown that Wegovy® Pill users can lose up to 17% of their initial body weight. For a 200lb individual, that equals up to 34lbs. However, individual results may vary based on your prescribed dose, medical history, and lifestyle choices. For the best results, use the Wegovy® Pill with a reduced-calorie meal plan and regular exercise. If you feel that you’re not achieving your expected results, contact your prescriber to see what’s best for you.

How quickly can I lose weight with Wegovy®?

For the best results, the Wegovy® Pill should be used regularly for at least 6-12 months with a reduced-calorie meal plan and regular exercise. Clinical trials show an average of 17% weight loss within 64 weeks, or about 14-15 months, with many participants showing up to 5% weight loss within 12 weeks. However, this can vary depending on your health history, exercise level, and diet. Do not abruptly stop taking Wegovy® Pill, as your appetite and weight may return just as quickly.

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Additional resources