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Low Dose Naltrexone

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Unlike other treatments, Low Dose Naltrexone (LDN) has been shown to work with your immune system to potentially reduce pain, restore energy, and improve quality of life.

Starting at $35

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LDN Benefits

LOW DOSE NALTREXONE BENEFITS

Regain control of your health

  • Prevents your immune system from attacking your organs & tissues
  • Shown to support positive moods with up to 3x increase in endorphin levels
  • Lowers pro-inflammatory factors in the body, promoting overall wellness
  • May reduce fatigue to restore energy levels
  • May support weight loss when combined with a healthy lifestyle
  • Clinically shown to reduce chronic pain
  • Tested for purity by US-licensed pharmacies
See the longevity science

Low Dose Naltrexone has not been approved by the FDA for these uses, but there are multiple studies that have shown these benefits.

LOW DOSE NALTREXONE – LDN

Background and history

  • Prescribed for 40+ years with outstanding safety record
  • FDA approved to treat opiate dependencies and obesity
  • Dosages below 10mg/day are considered “Low Dose Naltrexone” (LDN)—4.5mg/day is the most common
  • Exhibits novel and paradoxical effects for a variety of conditions
  • Used to treat autoimmune diseases and viral infections since 1985
  • Explore which starting dose is right for you
  • Read more on our LDN Blog or What is LDN?
LDN Background and History

Science-backed treatment, real results

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91% of patients felt improvement by their second check-in

Mood

69% reported improved moods

72% saw a reduction in inflammation

Reduce

75% experienced reduced pain

*Actual results may vary. Data was self-reported by 1,412 surveyed customers who checked in with their provider on their second check-in between 4/1/23 and 4/1/24. All respondents are AgelessRx Low Dose Naltrexone customers who were approved for a prescription after completing an assessment with a medical provider.

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Science of Low Dose Naltrexone (LDN)

Real results from people like you

LDN is the best help for any cravings and aiding weight loss, as well as helping with mood and inflammation…. AgelessRx makes expensive science-based biohacking affordable and accessible.

Just started LDN and it is a lifesaver! Gave me back energy and functionality that I haven’t felt in years.

I’m able to exercise in a normal pattern and [my] brain fog has gotten a lot better too. I have experienced things that I didn’t think I would ever regain.

LDN Research Trust 2023 Member

*The testimonials on this page are from real AgelessRx customers sourced from Trustpilot.com. Individual results may vary. Testimonials are not a guarantee of future results.

How it works

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Simple consultation

Connect with our US-licensed medical prescribers online to see if Low Dose Naltrexone is right for you, no office visit required.

Free shipping

If approved, your prescription will be fulfilled by one of our US-licensed, 503A certified pharmacy partners and rigorously inspected for quality before arriving at your doorstep in 5 days or less.*

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Continuous support

Enjoy ongoing access to providers, easy refills, and direct updates from your prescriber, ensuring support throughout your journey.

*Shipping times do not include pharmacy processing or doctor approval; your AgelessRx provider will take 1-2 days to review your request and send to our partner pharmacy, who will take an additional 2-3 days to process. Shipping times may be affected by regional variability. Temperature-sensitive medications are subject to state and federal requirements and may take longer to ship.

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Quarterly Monthly
Quarterly 1.5mg Protocol
$35 / month billed $105 quarterly | free shipping
  • 1.5mg strength capsules

  • Standard titration process

  • Ramp up to 4.5mg daily dose or as prescribed

  • 3-month supply

CODE LDN20$20 off first quarter & FREE medical evaluation

Quarterly 0.5mg Protocol
$35 / month billed $105 quarterly | free shipping
  • 0.5mg strength capsules

  • Slower titration process

  • Ramp up to 4.5mg daily dose or as prescribed

  • 3-month supply

CODE LDN20$20 off first quarter & FREE medical evaluation

Monthly 1.5mg Protocol
$45 / month billed monthly | free shipping
  • 1.5mg strength capsules
  • Standard titration process
  • Ramp up to 4.5mg daily dose or as prescribed
  • 1-month supply

A medical professional may recommend a different dose during medical intake process

You can request daily dose adjustments between refills

You will be automatically billed & sent refills based on your plan

You can pause or cancel at any time before your next shipment

* Prescription products require an online evaluation with a licensed medical professional who will determine if a prescription is appropriate. See below for important safety information. Benefits outlined on AgelessRx.com are based on 3rd party studies. Medication is offered as a subscription service which you can cancel at any time. Actual product packaging may appear differently than shown.

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FAQs


How often do I take Low Dose Naltrexone – LDN?

You will always take your LDN dose every night before bedtime (between 9pm and 2am). To start, you will take 1 capsule (0.5mg or 1.5mg), and slowly ramp up to the target dose (3.0mg or 4.5mg).


How can I monitor my response to LDN?

In the short term, patients report an improvement or reduction of symptoms related to inflammation and rampant oxidative stress, such as joint pain, back pain, fatigue, weight gain, and more.


What form of LDN will I receive?

AgelessRx provides LDN in capsule form with sucrose as the standard filler.

If you are taking LDN for the first time, you will start out with a lower dose (0.5mg or 1.5mg) and slowly work up to the prescribed dose (3.0mg or 4.5mg) over a 20-day to 3-month period, depending on your titration schedule.

See all FAQs

Important safety information and common side effects


When starting LDN, you may experience mild to moderate levels of the below-listed side effects during the first 3 to 5 days. These typically diminish on their own as your body adjusts to the medication, usually by the fifth day.

If you are on thyroid medication, you may need to monitor your thyroid levels more closely as you start LDN. IF you develop symptoms of hyperthyroidism while taking LDN, such as heart racing, increased anxiety, restlessness, or trouble sleeping, please stop LDN and talk to the prescriber for your thyroid medication.

Note: You MUST stop taking LDN at least 48 hours before any surgical or diagnostic procedure requiring sedation. If you’re scheduled for a procedure and not sure whether you should stop taking LDN, please ask the doctor ordering the test or procedure. Additionally, you CANNOT resume LDN until at least 48 hours after you have finished any prescribed medication for the procedure.

Most common LDN side effects

  • Vivid dreams
  • Mild anxiety
  • Insomnia
  • Headache

For a full list of possible side effects, click here.

Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.